Non-Alcoholic Fatty Liver Disease in Long-Term Type 2 Diabetes: Role of rs738409 <i>PNPLA3</i> and rs499765 <i>FGF21</i> Polymorphisms and Serum Biomarkers

Non-Alcoholic Fatty Liver Disease in Long-Term Type 2 Diabetes: Role of rs738409 <i>PNPLA3</i> and rs499765 <i>FGF21</i> Polymorphisms and Serum Biomarkers

Fibroblast growth factor 21 (FGF21) signaling and genetic factors are involved in non-alcoholic fatty liver disease (NAFLD) pathogenesis. However, these factors have rarely been studied in type 2 diabetes mellitus (T2D) patients from admixed populations such as in those of Brazil. Therefore, we aime...

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Bibliographic Details
Main Authors: Mauy Frujuello Mana, Maria Cândida R. Parisi, Maria Lucia Correa-Giannella, Arnaldo Moura Neto, Ademar Yamanaka, Marlone Cunha-Silva, Ana Mercedes Cavaleiro, Cristina Rodrigues dos Santos, Célia Regina Pavan, Tiago Sevá-Pereira, Sergio S. J. Dertkigil, Daniel F. Mazo
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Molecules
Subjects:
non-alcoholic fatty liver disease
type 2 diabetes
liver fibrosis
genetic polymorphisms
biomarkers
elastography
Online Access:https://www.mdpi.com/1420-3049/27/10/3193

Internet

https://www.mdpi.com/1420-3049/27/10/3193

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