The Effect of Cycloplegia on Ocular Alignment and AC/A Ratio

Abstract Purpose: The present study sets out to investigate the effect of cyclopentolate-induced cycloplegia on distance and near deviation and the accommodative convergence/accommodation (AC/A) ratio. Methods: This prospective study was performed on 30 subjects. The inclusion criteria included a la...

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Main Authors: Amir Asharlous, Hassan Hashemi, Abbasali Yekta, Alireza Riazifar, Asgar Doostdar, Mahsa Sadri, Amir Rakhshan, Hadi Ostadimoghaddam, Mehdi Khabazkhoob
Format: Article
Language:English
Published: Knowledge E 2024-03-01
Series:Journal of Ophthalmic & Vision Research
Subjects:
Online Access:https://doi.org/10.18502/jovr.v19i1.15442
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author Amir Asharlous
Hassan Hashemi
Abbasali Yekta
Alireza Riazifar
Asgar Doostdar
Mahsa Sadri
Amir Rakhshan
Hadi Ostadimoghaddam
Mehdi Khabazkhoob
author_facet Amir Asharlous
Hassan Hashemi
Abbasali Yekta
Alireza Riazifar
Asgar Doostdar
Mahsa Sadri
Amir Rakhshan
Hadi Ostadimoghaddam
Mehdi Khabazkhoob
author_sort Amir Asharlous
collection DOAJ
description Abstract Purpose: The present study sets out to investigate the effect of cyclopentolate-induced cycloplegia on distance and near deviation and the accommodative convergence/accommodation (AC/A) ratio. Methods: This prospective study was performed on 30 subjects. The inclusion criteria included a lack of any active ocular pathology and systemic diseases, no history of ocular surgery, and nonuse of various medications. Refraction, near and distance deviation were measured for all subjects, and the same examinations were repeated after the administration of two drops of cyclopentolate 1% to both eyes. Results: The obtained data from 30 subjects, including 19 males, with a mean age of 22.53 ± 1.74 years were analyzed. The mean ± SD of near deviation in dry and cycloplegic conditions were –6.9 ± 8.1 and +6.4 ± 9.1 prism diopters, respectively, which were statistically significant (P < 0.001). Distance deviation in cycloplegic conditions demonstrated an average difference of 0.8 prism diopters, compared to dry conditions (P < 0.001). AC/A ratios were 4.7 ± 2.5 and 9.7 ± 3.9 (Δ/D) in non-cycloplegic and cycloplegic conditions, respectively, which was a statistically significant difference (P < 0.001). The multiple regression indicated that among all under study variables, refraction (B coefficient: –2.4; P < 0.001) and near pre-cycloplegic deviation (B coefficient: 0.56; P < 0.001) were significantly associated with post-cycloplegic near deviation. Conclusion: The results of this study indicated that cycloplegia causes a considerable esophoric shift in near deviation and a negligible esophoric shift in distance deviation. As a result, the AC/A ratio demonstrated a significant increase due to unequal changes in near and distance deviation.
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spelling doaj.art-5da0ba178d84487cb16bb3116dbc795c2024-04-02T05:30:46ZengKnowledge EJournal of Ophthalmic & Vision Research2008-20102008-322X2024-03-01191828710.18502/jovr.v19i1.15442jovr.v19i1.15442The Effect of Cycloplegia on Ocular Alignment and AC/A RatioAmir Asharlous0Hassan Hashemi1Abbasali Yekta2Alireza Riazifar3Asgar Doostdar4Mahsa Sadri5Amir Rakhshan6Hadi Ostadimoghaddam7Mehdi Khabazkhoob8 Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran Department of Optometry, Mashhad University of Medical Sciences, Mashhad, Iran Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran Department of Foreign Languages, Tehran University of Medical Sciences, Tehran, Iran Refractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Department of Basic Sciences, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, IranAbstract Purpose: The present study sets out to investigate the effect of cyclopentolate-induced cycloplegia on distance and near deviation and the accommodative convergence/accommodation (AC/A) ratio. Methods: This prospective study was performed on 30 subjects. The inclusion criteria included a lack of any active ocular pathology and systemic diseases, no history of ocular surgery, and nonuse of various medications. Refraction, near and distance deviation were measured for all subjects, and the same examinations were repeated after the administration of two drops of cyclopentolate 1% to both eyes. Results: The obtained data from 30 subjects, including 19 males, with a mean age of 22.53 ± 1.74 years were analyzed. The mean ± SD of near deviation in dry and cycloplegic conditions were –6.9 ± 8.1 and +6.4 ± 9.1 prism diopters, respectively, which were statistically significant (P < 0.001). Distance deviation in cycloplegic conditions demonstrated an average difference of 0.8 prism diopters, compared to dry conditions (P < 0.001). AC/A ratios were 4.7 ± 2.5 and 9.7 ± 3.9 (Δ/D) in non-cycloplegic and cycloplegic conditions, respectively, which was a statistically significant difference (P < 0.001). The multiple regression indicated that among all under study variables, refraction (B coefficient: –2.4; P < 0.001) and near pre-cycloplegic deviation (B coefficient: 0.56; P < 0.001) were significantly associated with post-cycloplegic near deviation. Conclusion: The results of this study indicated that cycloplegia causes a considerable esophoric shift in near deviation and a negligible esophoric shift in distance deviation. As a result, the AC/A ratio demonstrated a significant increase due to unequal changes in near and distance deviation.https://doi.org/10.18502/jovr.v19i1.15442convergence mydriatics strabismus
spellingShingle Amir Asharlous
Hassan Hashemi
Abbasali Yekta
Alireza Riazifar
Asgar Doostdar
Mahsa Sadri
Amir Rakhshan
Hadi Ostadimoghaddam
Mehdi Khabazkhoob
The Effect of Cycloplegia on Ocular Alignment and AC/A Ratio
Journal of Ophthalmic & Vision Research
convergence mydriatics strabismus
title The Effect of Cycloplegia on Ocular Alignment and AC/A Ratio
title_full The Effect of Cycloplegia on Ocular Alignment and AC/A Ratio
title_fullStr The Effect of Cycloplegia on Ocular Alignment and AC/A Ratio
title_full_unstemmed The Effect of Cycloplegia on Ocular Alignment and AC/A Ratio
title_short The Effect of Cycloplegia on Ocular Alignment and AC/A Ratio
title_sort effect of cycloplegia on ocular alignment and ac a ratio
topic convergence mydriatics strabismus
url https://doi.org/10.18502/jovr.v19i1.15442
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