Clinical analysis of women with ovarian pregnancy: a retrospective case–control study
Abstract Background To address the clinical features and potential risk factors of ovarian pregnancy (OP). Methods In this retrospective case–control study performed in West China Second University Hospital from March 17, 2005 to December 8, 2018, 146 OP patients were selected as a case group, 292 p...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-10-01
|
| Series: | BMC Pregnancy and Childbirth |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12884-022-05099-8 |
| _version_ | 1798029973257191424 |
|---|---|
| author | Hongyi Li Yu Liu Yang Yang Xia Zhao Xiaorong Qi |
| author_facet | Hongyi Li Yu Liu Yang Yang Xia Zhao Xiaorong Qi |
| author_sort | Hongyi Li |
| collection | DOAJ |
| description | Abstract Background To address the clinical features and potential risk factors of ovarian pregnancy (OP). Methods In this retrospective case–control study performed in West China Second University Hospital from March 17, 2005 to December 8, 2018, 146 OP patients were selected as a case group, 292 patients with tubal pregnancy (TP) and 292 women with intrauterine pregnancy (IUP) were matched as controls at a ratio of 1:2:2. Results When compared with TP patients, OP patients tend to have worse clinical complications (hemorrhagic shock (7.41% vs 2.89%), rupture of pregnancy sac (54.07% vs 37.78%), hemoperitoneum (363.1 ± 35.46 ml vs 239.3 ± 27.61 ml) and increased need for emergency laparotomy (9.60% vs 3.97%) at an early gestational age. Assisted reproductive technology (ART) (adjusted OR1 2.08, 95%CI 1.04 to 4.18; adjusted OR2 2.59, 95%CI 1.25 to 5.37) and intrauterine contraceptive device (IUD) use (adjusted OR1 2.19, 95%CI 1.10 to 4.36; adjusted OR2 2.77, 95%CI 1.74 to 5.71) may be risk factors for ovarian ectopic pregnancy as compared to the control groups of TP and IUP patients. Conclusions OP patients tend to have more severe clinical complications and this study has identified ART and IUD use as potential risk factors for OP. Results of this study may contribute to improve the understanding of OP and promote early surgical intervention. |
| first_indexed | 2024-04-11T19:32:53Z |
| format | Article |
| id | doaj.art-5da4f82c9c3b43498ce41054fb01266c |
| institution | Directory Open Access Journal |
| issn | 1471-2393 |
| language | English |
| last_indexed | 2024-04-11T19:32:53Z |
| publishDate | 2022-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pregnancy and Childbirth |
| spelling | doaj.art-5da4f82c9c3b43498ce41054fb01266c2022-12-22T04:06:56ZengBMCBMC Pregnancy and Childbirth1471-23932022-10-012211910.1186/s12884-022-05099-8Clinical analysis of women with ovarian pregnancy: a retrospective case–control studyHongyi Li0Yu Liu1Yang Yang2Xia Zhao3Xiaorong Qi4Department of Gynecology and Obstetrics, Development and Related Disease of Women and Children Key Laboratory of Sichuan Province, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan UniversityDepartment of Gynecology and Obstetrics, Development and Related Disease of Women and Children Key Laboratory of Sichuan Province, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan UniversityDepartment of Gynecology and Obstetrics, Development and Related Disease of Women and Children Key Laboratory of Sichuan Province, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan UniversityDepartment of Gynecology and Obstetrics, Development and Related Disease of Women and Children Key Laboratory of Sichuan Province, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan UniversityDepartment of Gynecology and Obstetrics, Development and Related Disease of Women and Children Key Laboratory of Sichuan Province, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan UniversityAbstract Background To address the clinical features and potential risk factors of ovarian pregnancy (OP). Methods In this retrospective case–control study performed in West China Second University Hospital from March 17, 2005 to December 8, 2018, 146 OP patients were selected as a case group, 292 patients with tubal pregnancy (TP) and 292 women with intrauterine pregnancy (IUP) were matched as controls at a ratio of 1:2:2. Results When compared with TP patients, OP patients tend to have worse clinical complications (hemorrhagic shock (7.41% vs 2.89%), rupture of pregnancy sac (54.07% vs 37.78%), hemoperitoneum (363.1 ± 35.46 ml vs 239.3 ± 27.61 ml) and increased need for emergency laparotomy (9.60% vs 3.97%) at an early gestational age. Assisted reproductive technology (ART) (adjusted OR1 2.08, 95%CI 1.04 to 4.18; adjusted OR2 2.59, 95%CI 1.25 to 5.37) and intrauterine contraceptive device (IUD) use (adjusted OR1 2.19, 95%CI 1.10 to 4.36; adjusted OR2 2.77, 95%CI 1.74 to 5.71) may be risk factors for ovarian ectopic pregnancy as compared to the control groups of TP and IUP patients. Conclusions OP patients tend to have more severe clinical complications and this study has identified ART and IUD use as potential risk factors for OP. Results of this study may contribute to improve the understanding of OP and promote early surgical intervention.https://doi.org/10.1186/s12884-022-05099-8Ovarian pregnancyTubal pregnancyClinical complicationsRisk factorsLaparoscopy |
| spellingShingle | Hongyi Li Yu Liu Yang Yang Xia Zhao Xiaorong Qi Clinical analysis of women with ovarian pregnancy: a retrospective case–control study BMC Pregnancy and Childbirth Ovarian pregnancy Tubal pregnancy Clinical complications Risk factors Laparoscopy |
| title | Clinical analysis of women with ovarian pregnancy: a retrospective case–control study |
| title_full | Clinical analysis of women with ovarian pregnancy: a retrospective case–control study |
| title_fullStr | Clinical analysis of women with ovarian pregnancy: a retrospective case–control study |
| title_full_unstemmed | Clinical analysis of women with ovarian pregnancy: a retrospective case–control study |
| title_short | Clinical analysis of women with ovarian pregnancy: a retrospective case–control study |
| title_sort | clinical analysis of women with ovarian pregnancy a retrospective case control study |
| topic | Ovarian pregnancy Tubal pregnancy Clinical complications Risk factors Laparoscopy |
| url | https://doi.org/10.1186/s12884-022-05099-8 |
| work_keys_str_mv | AT hongyili clinicalanalysisofwomenwithovarianpregnancyaretrospectivecasecontrolstudy AT yuliu clinicalanalysisofwomenwithovarianpregnancyaretrospectivecasecontrolstudy AT yangyang clinicalanalysisofwomenwithovarianpregnancyaretrospectivecasecontrolstudy AT xiazhao clinicalanalysisofwomenwithovarianpregnancyaretrospectivecasecontrolstudy AT xiaorongqi clinicalanalysisofwomenwithovarianpregnancyaretrospectivecasecontrolstudy |