<i>trans</i>-3-Benzyloxycarbonylamino-1-methyl-3-(methylcarbamoyl)azetidine-1-oxide
<i>trans</i>-3-Benzyloxycarbonylamino-1-methyl-3-(methylcarbamoyl)azetidine-1-oxide was prepared by stereoselective oxidation of the corresponding azetidine precursor. The stable molecule was characterized in a low-polarity solution by IR, <sup>1</sup>H-NMR and <sup>13&...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-09-01
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Series: | Molbank |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-8599/2023/3/M1726 |
Summary: | <i>trans</i>-3-Benzyloxycarbonylamino-1-methyl-3-(methylcarbamoyl)azetidine-1-oxide was prepared by stereoselective oxidation of the corresponding azetidine precursor. The stable molecule was characterized in a low-polarity solution by IR, <sup>1</sup>H-NMR and <sup>13</sup>C-NMR, and in the solid state as a co-crystal with water by X-Ray diffraction. The <i>N</i>-oxide function made a strong intramolecular 7-membered ring hydrogen bond with the methyl amide NH in solution and formed an intermolecular H-bond with the carbamate NH in a neighboring molecule in the solid state. |
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ISSN: | 1422-8599 |