Tentative exploration of pharmacodynamic substances: Pharmacological effects, chemical compositions, and multi-components pharmacokinetic characteristics of ESZWD in CHF-HKYd rats

Tentative exploration of pharmacodynamic substances: Pharmacological effects, chemical compositions, and multi-components pharmacokinetic characteristics of ESZWD in CHF-HKYd rats

The chemical components of Xin'an famous prescription Ershen Zhenwu Decoction (ESZWD) are still unclear. The results showed that ESZWD could significantly reduce left ventricular end diastolic diameter, decrease N-terminal pro-brain natriuretic peptide (NT-proBNP), angiotensinII, aldosterone, r...

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Bibliographic Details
Main Authors:	Li-li Hong, Yan Zhao, Wei-dong Chen, Chen-yu Yang, Guo-zhuan Li, Hong-song Wang, Xiao-yu Cheng
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-09-01
Series:	Frontiers in Cardiovascular Medicine
Subjects:	Ershen Zhenwu Decoction chronic heart failure with heart-kidney Yang deficiency UPLC/Q-TOF-MS pharmacokinetic pharmacodynamic substances
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2022.913661/full

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