Cyclopia: A Rare Congenital Malformation
Cyclopia is a rare and lethal congenital anomaly of the forebrain system, resulting from incomplete cleavage of prosencephalon into right and left hemispheres occurring between the 18th and the 28th day of gestation. Approximately 1.05 in 100,000 births are identified as infants with cyclopia, inclu...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Nobel Medical College Teaching Hospital
2018-12-01
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| Series: | Journal of Nobel Medical College |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/JoNMC/article/view/22311 |
| _version_ | 1818037182066065408 |
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| author | Sunil Kumar Yadav Arun Giri Vijay Kumar sah |
| author_facet | Sunil Kumar Yadav Arun Giri Vijay Kumar sah |
| author_sort | Sunil Kumar Yadav |
| collection | DOAJ |
| description | Cyclopia is a rare and lethal congenital anomaly of the forebrain system, resulting from incomplete cleavage of prosencephalon into right and left hemispheres occurring between the 18th and the 28th day of gestation. Approximately 1.05 in 100,000 births are identified as infants with cyclopia, including stillbirths. Many teratogenic factors are identified as the causative factors for this anomaly which include irregular cholesterol biosynthesis, radiation exposure, viruses, alcohol intake and maternal diabetes. Many authors also suggest genetic etiology of this illness. We report a case of 35 year old lady G7P6L5 with previous history of normal vaginal delivery who presented to us in second stage of labor. She delivered a male baby with a large head, a median single eye and absent nose with intact mouth. The baby died soon after the birth. This case is presented because of its rarity. Early ultrasound diagnostics and proper management of this anomaly must be emphasized most strongly to prevent complication associated with this condition. |
| first_indexed | 2024-12-10T07:22:46Z |
| format | Article |
| id | doaj.art-5daec63ee7294704afd711299628c031 |
| institution | Directory Open Access Journal |
| issn | 2091-2331 2091-234X |
| language | English |
| last_indexed | 2024-12-10T07:22:46Z |
| publishDate | 2018-12-01 |
| publisher | Nobel Medical College Teaching Hospital |
| record_format | Article |
| series | Journal of Nobel Medical College |
| spelling | doaj.art-5daec63ee7294704afd711299628c0312022-12-22T01:57:47ZengNobel Medical College Teaching HospitalJournal of Nobel Medical College2091-23312091-234X2018-12-0172707310.3126/jonmc.v7i2.2231122311Cyclopia: A Rare Congenital MalformationSunil Kumar Yadav0Arun Giri1Vijay Kumar sah2Department of Pediatrics and Neonatology, Nobel Medical College and Teaching HospitalDepartment of Pediatrics and Neonatology, Nobel Medical College and Teaching HospitalDepartment of Pediatrics and Neonatology, Nobel Medical College and Teaching HospitalCyclopia is a rare and lethal congenital anomaly of the forebrain system, resulting from incomplete cleavage of prosencephalon into right and left hemispheres occurring between the 18th and the 28th day of gestation. Approximately 1.05 in 100,000 births are identified as infants with cyclopia, including stillbirths. Many teratogenic factors are identified as the causative factors for this anomaly which include irregular cholesterol biosynthesis, radiation exposure, viruses, alcohol intake and maternal diabetes. Many authors also suggest genetic etiology of this illness. We report a case of 35 year old lady G7P6L5 with previous history of normal vaginal delivery who presented to us in second stage of labor. She delivered a male baby with a large head, a median single eye and absent nose with intact mouth. The baby died soon after the birth. This case is presented because of its rarity. Early ultrasound diagnostics and proper management of this anomaly must be emphasized most strongly to prevent complication associated with this condition.https://www.nepjol.info/index.php/JoNMC/article/view/22311cyclopiasingle eyelarge head |
| spellingShingle | Sunil Kumar Yadav Arun Giri Vijay Kumar sah Cyclopia: A Rare Congenital Malformation Journal of Nobel Medical College cyclopia single eye large head |
| title | Cyclopia: A Rare Congenital Malformation |
| title_full | Cyclopia: A Rare Congenital Malformation |
| title_fullStr | Cyclopia: A Rare Congenital Malformation |
| title_full_unstemmed | Cyclopia: A Rare Congenital Malformation |
| title_short | Cyclopia: A Rare Congenital Malformation |
| title_sort | cyclopia a rare congenital malformation |
| topic | cyclopia single eye large head |
| url | https://www.nepjol.info/index.php/JoNMC/article/view/22311 |
| work_keys_str_mv | AT sunilkumaryadav cyclopiaararecongenitalmalformation AT arungiri cyclopiaararecongenitalmalformation AT vijaykumarsah cyclopiaararecongenitalmalformation |