Effect of gut microbiome-derived metabolites and extracellular vesicles on hepatocyte functions in a gut-liver axis chip

Abstract Metabolism, is a complex process involving the gut and the liver tissue, is difficult to be reproduced in vitro with conventional single cell culture systems. To tackle this challenge, we developed a gut-liver-axis chip consisting of the gut epithelial cell chamber and three-dimensional (3D...

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Dettagli Bibliografici
Autori principali: Seong Goo Kang, Yoon Young Choi, Sung Jun Mo, Tae Hyeon Kim, Jang Ho Ha, Dong Ki Hong, Hayera Lee, Soo Dong Park, Jae-Jung Shim, Jung-Lyoul Lee, Bong Geun Chung
Natura: Articolo
Lingua:English
Pubblicazione: SpringerOpen 2023-01-01
Serie:Nano Convergence
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Accesso online:https://doi.org/10.1186/s40580-022-00350-6