Effect of gut microbiome-derived metabolites and extracellular vesicles on hepatocyte functions in a gut-liver axis chip

Effect of gut microbiome-derived metabolites and extracellular vesicles on hepatocyte functions in a gut-liver axis chip

Abstract Metabolism, is a complex process involving the gut and the liver tissue, is difficult to be reproduced in vitro with conventional single cell culture systems. To tackle this challenge, we developed a gut-liver-axis chip consisting of the gut epithelial cell chamber and three-dimensional (3D...

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Bibliographic Details
Main Authors: Seong Goo Kang, Yoon Young Choi, Sung Jun Mo, Tae Hyeon Kim, Jang Ho Ha, Dong Ki Hong, Hayera Lee, Soo Dong Park, Jae-Jung Shim, Jung-Lyoul Lee, Bong Geun Chung
Format: Article
Language:English
Published: SpringerOpen 2023-01-01
Series:Nano Convergence
Subjects:
Gut-liver axis chip
Metabolites
Microbiome
Exosome
Liver function
Online Access:https://doi.org/10.1186/s40580-022-00350-6

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