Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products
Currently, the limited number of antifungals available for treating fungal infections, the increased multiresistance, and the adverse effects are the major obstacles for fungal infection therapy. Recently, emergent opportunistic fungus infections have been described and reinforced the requirement of...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2014-06-01
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Series: | Frontiers in Marine Science |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmars.2014.00012/full |
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author | Luciana eTerra Paula eAbreu Valéria L. Teixeira Izabel C.N.P. Paixão Rebeca ePereira Bruno eLeal Andre eLourenço Pabulo Henrique eRampelotto Helena C. Castro |
author_facet | Luciana eTerra Paula eAbreu Valéria L. Teixeira Izabel C.N.P. Paixão Rebeca ePereira Bruno eLeal Andre eLourenço Pabulo Henrique eRampelotto Helena C. Castro |
author_sort | Luciana eTerra |
collection | DOAJ |
description | Currently, the limited number of antifungals available for treating fungal infections, the increased multiresistance, and the adverse effects are the major obstacles for fungal infection therapy. Recently, emergent opportunistic fungus infections have been described and reinforced the requirement of researches aimed at the discovery of novel antifungal agents. Herein we reviewed the main topics about fungi and its related infections, the antifungals available, their mechanism of action and resistance profile. In this work, we pointed fungi as a biotechnological target for finding new options in alternative sources such as marine products with new mechanisms of action to allow treating these dangerous infections. |
first_indexed | 2024-04-12T00:56:44Z |
format | Article |
id | doaj.art-5db65289bd824f2da72340be812e60b3 |
institution | Directory Open Access Journal |
issn | 2296-7745 |
language | English |
last_indexed | 2024-04-12T00:56:44Z |
publishDate | 2014-06-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Marine Science |
spelling | doaj.art-5db65289bd824f2da72340be812e60b32022-12-22T03:54:35ZengFrontiers Media S.A.Frontiers in Marine Science2296-77452014-06-01110.3389/fmars.2014.0001287266Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine productsLuciana eTerra0Paula eAbreu1Valéria L. Teixeira2Izabel C.N.P. Paixão3Rebeca ePereira4Bruno eLeal5Andre eLourenço6Pabulo Henrique eRampelotto7Helena C. Castro8Universidade Federal FluminenseUniversidade Federal do Rio de JaneiroUniversidade Federal FluminenseUniversidade Federal FluminenseUniversidade Federal FluminenseUniversidade Federal FluminenseUniversidade Federal FluminenseFederal University of PampaUniversidade Federal FluminenseCurrently, the limited number of antifungals available for treating fungal infections, the increased multiresistance, and the adverse effects are the major obstacles for fungal infection therapy. Recently, emergent opportunistic fungus infections have been described and reinforced the requirement of researches aimed at the discovery of novel antifungal agents. Herein we reviewed the main topics about fungi and its related infections, the antifungals available, their mechanism of action and resistance profile. In this work, we pointed fungi as a biotechnological target for finding new options in alternative sources such as marine products with new mechanisms of action to allow treating these dangerous infections.http://journal.frontiersin.org/Journal/10.3389/fmars.2014.00012/fullFungiInfectionAntifungalmarine productsapplied mycology |
spellingShingle | Luciana eTerra Paula eAbreu Valéria L. Teixeira Izabel C.N.P. Paixão Rebeca ePereira Bruno eLeal Andre eLourenço Pabulo Henrique eRampelotto Helena C. Castro Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products Frontiers in Marine Science Fungi Infection Antifungal marine products applied mycology |
title | Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products |
title_full | Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products |
title_fullStr | Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products |
title_full_unstemmed | Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products |
title_short | Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products |
title_sort | mycoses and antifungals reviewing the basis of a current problem that still is a biotechnological target for marine products |
topic | Fungi Infection Antifungal marine products applied mycology |
url | http://journal.frontiersin.org/Journal/10.3389/fmars.2014.00012/full |
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