Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products

Currently, the limited number of antifungals available for treating fungal infections, the increased multiresistance, and the adverse effects are the major obstacles for fungal infection therapy. Recently, emergent opportunistic fungus infections have been described and reinforced the requirement of...

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Main Authors: Luciana eTerra, Paula eAbreu, Valéria L. Teixeira, Izabel C.N.P. Paixão, Rebeca ePereira, Bruno eLeal, Andre eLourenço, Pabulo Henrique eRampelotto, Helena C. Castro
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Marine Science
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmars.2014.00012/full
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author Luciana eTerra
Paula eAbreu
Valéria L. Teixeira
Izabel C.N.P. Paixão
Rebeca ePereira
Bruno eLeal
Andre eLourenço
Pabulo Henrique eRampelotto
Helena C. Castro
author_facet Luciana eTerra
Paula eAbreu
Valéria L. Teixeira
Izabel C.N.P. Paixão
Rebeca ePereira
Bruno eLeal
Andre eLourenço
Pabulo Henrique eRampelotto
Helena C. Castro
author_sort Luciana eTerra
collection DOAJ
description Currently, the limited number of antifungals available for treating fungal infections, the increased multiresistance, and the adverse effects are the major obstacles for fungal infection therapy. Recently, emergent opportunistic fungus infections have been described and reinforced the requirement of researches aimed at the discovery of novel antifungal agents. Herein we reviewed the main topics about fungi and its related infections, the antifungals available, their mechanism of action and resistance profile. In this work, we pointed fungi as a biotechnological target for finding new options in alternative sources such as marine products with new mechanisms of action to allow treating these dangerous infections.
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spelling doaj.art-5db65289bd824f2da72340be812e60b32022-12-22T03:54:35ZengFrontiers Media S.A.Frontiers in Marine Science2296-77452014-06-01110.3389/fmars.2014.0001287266Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine productsLuciana eTerra0Paula eAbreu1Valéria L. Teixeira2Izabel C.N.P. Paixão3Rebeca ePereira4Bruno eLeal5Andre eLourenço6Pabulo Henrique eRampelotto7Helena C. Castro8Universidade Federal FluminenseUniversidade Federal do Rio de JaneiroUniversidade Federal FluminenseUniversidade Federal FluminenseUniversidade Federal FluminenseUniversidade Federal FluminenseUniversidade Federal FluminenseFederal University of PampaUniversidade Federal FluminenseCurrently, the limited number of antifungals available for treating fungal infections, the increased multiresistance, and the adverse effects are the major obstacles for fungal infection therapy. Recently, emergent opportunistic fungus infections have been described and reinforced the requirement of researches aimed at the discovery of novel antifungal agents. Herein we reviewed the main topics about fungi and its related infections, the antifungals available, their mechanism of action and resistance profile. In this work, we pointed fungi as a biotechnological target for finding new options in alternative sources such as marine products with new mechanisms of action to allow treating these dangerous infections.http://journal.frontiersin.org/Journal/10.3389/fmars.2014.00012/fullFungiInfectionAntifungalmarine productsapplied mycology
spellingShingle Luciana eTerra
Paula eAbreu
Valéria L. Teixeira
Izabel C.N.P. Paixão
Rebeca ePereira
Bruno eLeal
Andre eLourenço
Pabulo Henrique eRampelotto
Helena C. Castro
Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products
Frontiers in Marine Science
Fungi
Infection
Antifungal
marine products
applied mycology
title Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products
title_full Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products
title_fullStr Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products
title_full_unstemmed Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products
title_short Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products
title_sort mycoses and antifungals reviewing the basis of a current problem that still is a biotechnological target for marine products
topic Fungi
Infection
Antifungal
marine products
applied mycology
url http://journal.frontiersin.org/Journal/10.3389/fmars.2014.00012/full
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