Investigation of the Lipid-Lowering Mechanisms and Active Ingredients of Danhe Granule on Hyperlipidemia Based on Systems Pharmacology

Investigation of the Lipid-Lowering Mechanisms and Active Ingredients of Danhe Granule on Hyperlipidemia Based on Systems Pharmacology

ObjectiveInvestigate the active ingredients and underlying hypolipidemic mechanisms of Danhe granule (DHG).MethodsThe lipid-lowering effect of DHG was evaluated in hyperlipidemic hamsters induced by a high-fat diet. The ingredients absorbed into the blood after oral administration of DHG in hamsters...

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Bibliographic Details
Main Authors: Kuikui Chen, Zhaochen Ma, Xiaoning Yan, Jie Liu, Wenjuan Xu, Yueting Li, Yihang Dai, Yinhuan Zhang, Hongbin Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
Danhe granule
hyperlipidemia
systems pharmacology
mechanism
active ingredients
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00528/full

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