Systemic Sclerosis Manifesting Post-Radiotherapy: A Case Report
Morphoea is a chronic inflammatory disease of the skin and underlying tissues, characterised by fibrosis of the skin and subcutaneous tissue without systemic involvement. Radiation-induced morphoea is a rare, often unrecognised, chronically progressive form of radiation-associated localised sclerod...
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| Format: | Article |
| Language: | English |
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European Medical Journal
2023-08-01
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| Series: | European Medical Journal Dermatology |
| Online Access: | https://www.emjreviews.com/dermatology/article/systemic-sclerosis-manifesting-post-radiotherapy-a-case-report/ |
| _version_ | 1797393326345814016 |
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| author | Devanshi Nimbark Hita H. Mehta Manal D. Dave |
| author_facet | Devanshi Nimbark Hita H. Mehta Manal D. Dave |
| author_sort | Devanshi Nimbark |
| collection | DOAJ |
| description |
Morphoea is a chronic inflammatory disease of the skin and underlying tissues, characterised by fibrosis of the skin and subcutaneous tissue without systemic involvement. Radiation-induced morphoea is a rare, often unrecognised, chronically progressive form of radiation-associated localised scleroderma of the skin, infrequently progressing to systemic scleroderma. Systemic scleroderma is characterised by widespread tissue fibrosis along with systemic features, leading to an increased risk of malignancy compared to the general population. The authors present the case of a 67-year-old female, a previously diagnosed case of psoriasis developing squamous cell carcinoma on the ring finger with axillary nodal metastasis, who underwent radiotherapy, and subsequently developed symptoms of systemic sclerosis. This case is unique, as there are nominal reports on generalised morphoea converting to systemic sclerosis post-radiotherapy, along with exaggerated thickening of the skin over the side of radiotherapy. Thus, the authors report this rare side effect of radiotherapy. Treating physicians should always be vigilant in identifying these side effects after radiotherapy to prevent long-term sequelae of the disease, and minimise their impact on the patient’s quality of life. |
| first_indexed | 2024-03-09T00:02:00Z |
| format | Article |
| id | doaj.art-5dbbe2ded0544547bc48012a34c35268 |
| institution | Directory Open Access Journal |
| issn | 2054-6211 |
| language | English |
| last_indexed | 2024-03-09T00:02:00Z |
| publishDate | 2023-08-01 |
| publisher | European Medical Journal |
| record_format | Article |
| series | European Medical Journal Dermatology |
| spelling | doaj.art-5dbbe2ded0544547bc48012a34c352682023-12-12T16:56:32ZengEuropean Medical JournalEuropean Medical Journal Dermatology2054-62112023-08-0110.33590/emjdermatol/10303800Systemic Sclerosis Manifesting Post-Radiotherapy: A Case ReportDevanshi Nimbark0Hita H. Mehta1Manal D. Dave2Department of Dermatology, Venereology and Leprosy, Government Medical College, Sir Takhtasinhji Hospital, Bhavnagar, IndiaDepartment of Dermatology, Venereology and Leprosy, Government Medical College, Sir Takhtasinhji Hospital, Bhavnagar, IndiaDepartment of Dermatology, Venereology and Leprosy, Government Medical College, Sir Takhtasinhji Hospital, Bhavnagar, India Morphoea is a chronic inflammatory disease of the skin and underlying tissues, characterised by fibrosis of the skin and subcutaneous tissue without systemic involvement. Radiation-induced morphoea is a rare, often unrecognised, chronically progressive form of radiation-associated localised scleroderma of the skin, infrequently progressing to systemic scleroderma. Systemic scleroderma is characterised by widespread tissue fibrosis along with systemic features, leading to an increased risk of malignancy compared to the general population. The authors present the case of a 67-year-old female, a previously diagnosed case of psoriasis developing squamous cell carcinoma on the ring finger with axillary nodal metastasis, who underwent radiotherapy, and subsequently developed symptoms of systemic sclerosis. This case is unique, as there are nominal reports on generalised morphoea converting to systemic sclerosis post-radiotherapy, along with exaggerated thickening of the skin over the side of radiotherapy. Thus, the authors report this rare side effect of radiotherapy. Treating physicians should always be vigilant in identifying these side effects after radiotherapy to prevent long-term sequelae of the disease, and minimise their impact on the patient’s quality of life.https://www.emjreviews.com/dermatology/article/systemic-sclerosis-manifesting-post-radiotherapy-a-case-report/ |
| spellingShingle | Devanshi Nimbark Hita H. Mehta Manal D. Dave Systemic Sclerosis Manifesting Post-Radiotherapy: A Case Report European Medical Journal Dermatology |
| title | Systemic Sclerosis Manifesting Post-Radiotherapy: A Case Report |
| title_full | Systemic Sclerosis Manifesting Post-Radiotherapy: A Case Report |
| title_fullStr | Systemic Sclerosis Manifesting Post-Radiotherapy: A Case Report |
| title_full_unstemmed | Systemic Sclerosis Manifesting Post-Radiotherapy: A Case Report |
| title_short | Systemic Sclerosis Manifesting Post-Radiotherapy: A Case Report |
| title_sort | systemic sclerosis manifesting post radiotherapy a case report |
| url | https://www.emjreviews.com/dermatology/article/systemic-sclerosis-manifesting-post-radiotherapy-a-case-report/ |
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