Synaptic homeostasis transiently leverages Hebbian mechanisms for a multiphasic response to inactivity

Synaptic homeostasis transiently leverages Hebbian mechanisms for a multiphasic response to inactivity

Summary: Homeostatic regulation of synapses is vital for nervous system function and key to understanding a range of neurological conditions. Synaptic homeostasis is proposed to operate over hours to counteract the destabilizing influence of long-term potentiation (LTP) and long-term depression (LTD...

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Bibliographic Details
Main Authors: Simón(e) D. Sun, Daniel Levenstein, Boxing Li, Nataniel Mandelberg, Nicolas Chenouard, Benjamin S. Suutari, Sandrine Sanchez, Guoling Tian, John Rinzel, György Buzsáki, Richard W. Tsien
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Cell Reports
Subjects:
synapse
homeostasis
synaptic scaling
Hebbian plasticity
long-term potentiation
long-term depression
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724001670

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