CCL25/CCR9 interaction promotes the malignant behavior of salivary adenoid cystic carcinoma via the PI3K/AKT signaling pathway

CCL25/CCR9 interaction promotes the malignant behavior of salivary adenoid cystic carcinoma via the PI3K/AKT signaling pathway

Background CC chemokine receptor 9 (CCR9), an organ-specific chemokine receptor, interacts with its exclusive ligand CCL25 to promote tumor proliferation and metastasis. However, the effect of CCR9 on salivary adenoid cystic carcinoma (SACC) malignant behavior remains unknown. This study aimed to in...

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Bibliographic Details
Main Authors: Songling Chai, Zhihao Wen, Rongxin Zhang, Yuwen Bai, Jing Liu, Juanjuan Li, Wenyao Kongling, Weixian Chen, Fu Wang, Lu Gao
Format: Article
Language:English
Published: PeerJ Inc. 2022-08-01
Series:PeerJ
Subjects:
CCL25
CCR9
Salivary adenoid cystic carcinoma
Proliferation
Metastasis
PI3K/Akt
Online Access:https://peerj.com/articles/13844.pdf

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