Applications of X-Chromosome Short Tandem Repeats for Human Identification: A Review
The forensic DNA profiling technique has tremendously contributed to forensic human identification, an important aspect in forensic investigations. In instances whereby comparison samples are unavailable, utilization of short tandem repeats of X chromosome (X-STRs) may prove useful to resolve comple...
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| Format: | Article |
| Language: | English |
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University of Brawijaya
2023-01-01
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| Series: | Journal of Tropical Life Science |
| Subjects: | |
| Online Access: | https://jtrolis.ub.ac.id/index.php/jtrolis/article/view/2567 |
| _version_ | 1797688453312282624 |
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| author | Naji Arafat Mahat Aedrianee Reeza Alwi Faezah Mohd Salleh Seri Mirianti Ishar Mohammad Rahim Kamaluddin Mohd Radzniwan A. Rashid |
| author_facet | Naji Arafat Mahat Aedrianee Reeza Alwi Faezah Mohd Salleh Seri Mirianti Ishar Mohammad Rahim Kamaluddin Mohd Radzniwan A. Rashid |
| author_sort | Naji Arafat Mahat |
| collection | DOAJ |
| description | The forensic DNA profiling technique has tremendously contributed to forensic human identification, an important aspect in forensic investigations. In instances whereby comparison samples are unavailable, utilization of short tandem repeats of X chromosome (X-STRs) may prove useful to resolve complex kinship investigations involving missing persons and mass disasters. Despite such evidential values, the use of X-STRs during investigations remains scarce in many Southeast Asian countries including Malaysia, requiring concerted efforts for establishing forensic statistical support for its diverse populations (especially the admixture populations), standardizing core loci and procedure, improving the knowledge among practitioners as well as developing suitable standard operating procedure for incorporating X-STRs analysis in the overall DNA profiling framework. Hence, this review paper aims to highlight the developments, applications and population data of X-STRs, as well as its challenges and future insights for forensic casework. |
| first_indexed | 2024-03-12T01:31:12Z |
| format | Article |
| id | doaj.art-5dc376839bde48aaa5e473c5266161a4 |
| institution | Directory Open Access Journal |
| issn | 2087-5517 2527-4376 |
| language | English |
| last_indexed | 2024-03-12T01:31:12Z |
| publishDate | 2023-01-01 |
| publisher | University of Brawijaya |
| record_format | Article |
| series | Journal of Tropical Life Science |
| spelling | doaj.art-5dc376839bde48aaa5e473c5266161a42023-09-12T01:28:16ZengUniversity of BrawijayaJournal of Tropical Life Science2087-55172527-43762023-01-0113119321810.11594/jtls.13.01.192512Applications of X-Chromosome Short Tandem Repeats for Human Identification: A ReviewNaji Arafat Mahat0Aedrianee Reeza Alwi1Faezah Mohd Salleh2Seri Mirianti Ishar3Mohammad Rahim Kamaluddin4Mohd Radzniwan A. Rashid5Department of Chemistry, Faculty of Science, University Teknologi Malaysia, 81310 Skudai, JohorDepartment of Biosciences, Faculty of Science, Universiti Teknologi Malaysia (UTM), 81310 Johor Bahru, Johor, Malaysia.Department of Biosciences, Faculty of Science, Universiti Teknologi Malaysia (UTM), 81310 Johor Bahru, Johor, Malaysia.Faculty of Health Sciences, Universiti Kebangsaan Malaysia (UKM), 43600 Bangi, Selangor, Malaysia Psychology and Human Well Being Research Centre, Faculty of Social Sciences and Humanities, Universiti Kebangsaan Malaysia (UKM), 43600 Bangi, Selangor, Malaysia.Family Medicine Unit, Faculty of Medicine and Health Science, Universiti Sains Islam Malaysia (USIM), Bandar Baru Nilai 71800, Nilai, Negeri Sembilan, MalaysiaThe forensic DNA profiling technique has tremendously contributed to forensic human identification, an important aspect in forensic investigations. In instances whereby comparison samples are unavailable, utilization of short tandem repeats of X chromosome (X-STRs) may prove useful to resolve complex kinship investigations involving missing persons and mass disasters. Despite such evidential values, the use of X-STRs during investigations remains scarce in many Southeast Asian countries including Malaysia, requiring concerted efforts for establishing forensic statistical support for its diverse populations (especially the admixture populations), standardizing core loci and procedure, improving the knowledge among practitioners as well as developing suitable standard operating procedure for incorporating X-STRs analysis in the overall DNA profiling framework. Hence, this review paper aims to highlight the developments, applications and population data of X-STRs, as well as its challenges and future insights for forensic casework.https://jtrolis.ub.ac.id/index.php/jtrolis/article/view/2567complex kinshipforensic statistical parameteshuman identificationpopulation geneticsshort tandem repeatsx-chromosome |
| spellingShingle | Naji Arafat Mahat Aedrianee Reeza Alwi Faezah Mohd Salleh Seri Mirianti Ishar Mohammad Rahim Kamaluddin Mohd Radzniwan A. Rashid Applications of X-Chromosome Short Tandem Repeats for Human Identification: A Review Journal of Tropical Life Science complex kinship forensic statistical parametes human identification population genetics short tandem repeats x-chromosome |
| title | Applications of X-Chromosome Short Tandem Repeats for Human Identification: A Review |
| title_full | Applications of X-Chromosome Short Tandem Repeats for Human Identification: A Review |
| title_fullStr | Applications of X-Chromosome Short Tandem Repeats for Human Identification: A Review |
| title_full_unstemmed | Applications of X-Chromosome Short Tandem Repeats for Human Identification: A Review |
| title_short | Applications of X-Chromosome Short Tandem Repeats for Human Identification: A Review |
| title_sort | applications of x chromosome short tandem repeats for human identification a review |
| topic | complex kinship forensic statistical parametes human identification population genetics short tandem repeats x-chromosome |
| url | https://jtrolis.ub.ac.id/index.php/jtrolis/article/view/2567 |
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