Could herbal medicine (Soshihotang) be a new treatment option for COVID-19?: a narrative review

Background: While the world struggles under the coronavirus disease 2019 (COVID-19) pandemic, a variety of antiviral agents and symptomatic treatments are being administered to patients and urgent clinical trials are underway. Under these circumstances, it is important to explore various possibiliti...

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Main Authors: Seungwon Kwon, Wonhaeng Lee, Chul Jin, Insoo Jang, Woo-Sang Jung, Sang-Kwan Moon, Ki-Ho Cho
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Integrative Medicine Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213422020301128
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author Seungwon Kwon
Wonhaeng Lee
Chul Jin
Insoo Jang
Woo-Sang Jung
Sang-Kwan Moon
Ki-Ho Cho
author_facet Seungwon Kwon
Wonhaeng Lee
Chul Jin
Insoo Jang
Woo-Sang Jung
Sang-Kwan Moon
Ki-Ho Cho
author_sort Seungwon Kwon
collection DOAJ
description Background: While the world struggles under the coronavirus disease 2019 (COVID-19) pandemic, a variety of antiviral agents and symptomatic treatments are being administered to patients and urgent clinical trials are underway. Under these circumstances, it is important to explore various possibilities for the treatment of COVID-19 including herbal medicines. Among various herbal medicines, Soshihotang (SSHT, Xiao Chai Hu Tang in Chinese) has been prescribed to treat various viral diseases and is used in combination with other herbal medicines depending on the patient’s symptoms. Methods: For conducting the present review, we searched electronic databases focusing on the antiviral effect of SSHT in experimental and clinical study until April 2020. The search keywords included SSHT, constituents of SSHT, and antiviral effect. We also searched for materials related to topic directly from websites and published books. Based on these search results, we summarized the results of the included materials in the form of a narrative review. Results: In a number of recent clinical studies, treatment with SSHT improved the infection status of the respiratory and hepatobiliary systems, and experimental studies demonstrated the antiviral effect of SSHT and its components. Furthermore, SSHT are being used in China—where COVID-19 outbreak first took place—and offer a new option to treat COVID-19. Conclusion: Based on the present evidences, it is believed that SSHT is likely to be a new therapeutic option for COVID-19. Conducting further studies might provide improved understanding regarding the use of SSHT in treating COVID-19.
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spelling doaj.art-5dc4a39c9f6f4cbd856cb6b932d270312022-12-22T00:18:03ZengElsevierIntegrative Medicine Research2213-42202020-09-0193100480Could herbal medicine (Soshihotang) be a new treatment option for COVID-19?: a narrative reviewSeungwon Kwon0Wonhaeng Lee1Chul Jin2Insoo Jang3Woo-Sang Jung4Sang-Kwan Moon5Ki-Ho Cho6Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, South Korea; Corresponding author at: Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, South Korea.Leewonhaeng-Whajubmong Korean Medicine Clinic, Goyang, South KoreaDepartment of Korean Medicine Cardiology and Neurology, Graduate School, Kyung Hee University, Seoul, South KoreaDepartment of Internal Medicine, College of Korean Medicine, Woosuk University, Jeonju, South KoreaDepartment of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, South KoreaDepartment of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, South KoreaDepartment of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, South KoreaBackground: While the world struggles under the coronavirus disease 2019 (COVID-19) pandemic, a variety of antiviral agents and symptomatic treatments are being administered to patients and urgent clinical trials are underway. Under these circumstances, it is important to explore various possibilities for the treatment of COVID-19 including herbal medicines. Among various herbal medicines, Soshihotang (SSHT, Xiao Chai Hu Tang in Chinese) has been prescribed to treat various viral diseases and is used in combination with other herbal medicines depending on the patient’s symptoms. Methods: For conducting the present review, we searched electronic databases focusing on the antiviral effect of SSHT in experimental and clinical study until April 2020. The search keywords included SSHT, constituents of SSHT, and antiviral effect. We also searched for materials related to topic directly from websites and published books. Based on these search results, we summarized the results of the included materials in the form of a narrative review. Results: In a number of recent clinical studies, treatment with SSHT improved the infection status of the respiratory and hepatobiliary systems, and experimental studies demonstrated the antiviral effect of SSHT and its components. Furthermore, SSHT are being used in China—where COVID-19 outbreak first took place—and offer a new option to treat COVID-19. Conclusion: Based on the present evidences, it is believed that SSHT is likely to be a new therapeutic option for COVID-19. Conducting further studies might provide improved understanding regarding the use of SSHT in treating COVID-19.http://www.sciencedirect.com/science/article/pii/S2213422020301128COVID-19Herbal medicineSoshihotangShosaikotoXiao Chai Hu Tang
spellingShingle Seungwon Kwon
Wonhaeng Lee
Chul Jin
Insoo Jang
Woo-Sang Jung
Sang-Kwan Moon
Ki-Ho Cho
Could herbal medicine (Soshihotang) be a new treatment option for COVID-19?: a narrative review
Integrative Medicine Research
COVID-19
Herbal medicine
Soshihotang
Shosaikoto
Xiao Chai Hu Tang
title Could herbal medicine (Soshihotang) be a new treatment option for COVID-19?: a narrative review
title_full Could herbal medicine (Soshihotang) be a new treatment option for COVID-19?: a narrative review
title_fullStr Could herbal medicine (Soshihotang) be a new treatment option for COVID-19?: a narrative review
title_full_unstemmed Could herbal medicine (Soshihotang) be a new treatment option for COVID-19?: a narrative review
title_short Could herbal medicine (Soshihotang) be a new treatment option for COVID-19?: a narrative review
title_sort could herbal medicine soshihotang be a new treatment option for covid 19 a narrative review
topic COVID-19
Herbal medicine
Soshihotang
Shosaikoto
Xiao Chai Hu Tang
url http://www.sciencedirect.com/science/article/pii/S2213422020301128
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