Validation of human immunodeficiency virus diagnosis codes among women enrollees of a U.S. health plan

Abstract Background Efficiently identifying patients with human immunodeficiency virus (HIV) using administrative health care data (e.g., claims) can facilitate research on their quality of care and health outcomes. No prior study has validated the use of only ICD-10-CM HIV diagnosis codes to identi...

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Main Authors: Gaia Pocobelli, Malia Oliver, Ladia Albertson-Junkans, Gabrielle Gundersen, Aruna Kamineni
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Health Services Research
Subjects:
Online Access:https://doi.org/10.1186/s12913-024-10685-x
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author Gaia Pocobelli
Malia Oliver
Ladia Albertson-Junkans
Gabrielle Gundersen
Aruna Kamineni
author_facet Gaia Pocobelli
Malia Oliver
Ladia Albertson-Junkans
Gabrielle Gundersen
Aruna Kamineni
author_sort Gaia Pocobelli
collection DOAJ
description Abstract Background Efficiently identifying patients with human immunodeficiency virus (HIV) using administrative health care data (e.g., claims) can facilitate research on their quality of care and health outcomes. No prior study has validated the use of only ICD-10-CM HIV diagnosis codes to identify patients with HIV. Methods We validated HIV diagnosis codes among women enrolled in a large U.S. integrated health care system during 2010–2020. We examined HIV diagnosis code-based algorithms that varied by type, frequency, and timing of the codes in patients’ claims data. We calculated the positive predictive values (PPVs) and 95% confidence intervals (CIs) of the algorithms using a medical record-confirmed diagnosis of HIV as the gold standard. Results A total of 272 women with ≥ 1 HIV diagnosis code in the administrative claims data were identified and medical records were reviewed for all 272 women. The PPV of an algorithm classifying women as having HIV as of the first HIV diagnosis code during the observation period was 80.5% (95% CI: 75.4–84.8%), and it was 93.9% (95% CI: 90.0-96.3%) as of the second. Little additional increase in PPV was observed when a third code was required. The PPV of an algorithm based on ICD-10-CM-era codes was similar to one based on ICD-9-CM-era codes. Conclusion If the accuracy measure of greatest interest is PPV, our findings suggest that use of ≥ 2 HIV diagnosis codes to identify patients with HIV may perform well. However, health care coding practices may vary across settings, which may impact generalizability of our results.
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spelling doaj.art-5dc59452cf214e19ae59b04394617fce2024-03-05T18:05:28ZengBMCBMC Health Services Research1472-69632024-02-012411610.1186/s12913-024-10685-xValidation of human immunodeficiency virus diagnosis codes among women enrollees of a U.S. health planGaia Pocobelli0Malia Oliver1Ladia Albertson-Junkans2Gabrielle Gundersen3Aruna Kamineni4Kaiser Permanente Washington Health Research InstituteKaiser Permanente Washington Health Research InstituteKaiser Permanente Washington Health Research InstituteKaiser Permanente Washington Health Research InstituteKaiser Permanente Washington Health Research InstituteAbstract Background Efficiently identifying patients with human immunodeficiency virus (HIV) using administrative health care data (e.g., claims) can facilitate research on their quality of care and health outcomes. No prior study has validated the use of only ICD-10-CM HIV diagnosis codes to identify patients with HIV. Methods We validated HIV diagnosis codes among women enrolled in a large U.S. integrated health care system during 2010–2020. We examined HIV diagnosis code-based algorithms that varied by type, frequency, and timing of the codes in patients’ claims data. We calculated the positive predictive values (PPVs) and 95% confidence intervals (CIs) of the algorithms using a medical record-confirmed diagnosis of HIV as the gold standard. Results A total of 272 women with ≥ 1 HIV diagnosis code in the administrative claims data were identified and medical records were reviewed for all 272 women. The PPV of an algorithm classifying women as having HIV as of the first HIV diagnosis code during the observation period was 80.5% (95% CI: 75.4–84.8%), and it was 93.9% (95% CI: 90.0-96.3%) as of the second. Little additional increase in PPV was observed when a third code was required. The PPV of an algorithm based on ICD-10-CM-era codes was similar to one based on ICD-9-CM-era codes. Conclusion If the accuracy measure of greatest interest is PPV, our findings suggest that use of ≥ 2 HIV diagnosis codes to identify patients with HIV may perform well. However, health care coding practices may vary across settings, which may impact generalizability of our results.https://doi.org/10.1186/s12913-024-10685-xHIVPredictive value of testsValidation studyElectronic health recordsICD codes
spellingShingle Gaia Pocobelli
Malia Oliver
Ladia Albertson-Junkans
Gabrielle Gundersen
Aruna Kamineni
Validation of human immunodeficiency virus diagnosis codes among women enrollees of a U.S. health plan
BMC Health Services Research
HIV
Predictive value of tests
Validation study
Electronic health records
ICD codes
title Validation of human immunodeficiency virus diagnosis codes among women enrollees of a U.S. health plan
title_full Validation of human immunodeficiency virus diagnosis codes among women enrollees of a U.S. health plan
title_fullStr Validation of human immunodeficiency virus diagnosis codes among women enrollees of a U.S. health plan
title_full_unstemmed Validation of human immunodeficiency virus diagnosis codes among women enrollees of a U.S. health plan
title_short Validation of human immunodeficiency virus diagnosis codes among women enrollees of a U.S. health plan
title_sort validation of human immunodeficiency virus diagnosis codes among women enrollees of a u s health plan
topic HIV
Predictive value of tests
Validation study
Electronic health records
ICD codes
url https://doi.org/10.1186/s12913-024-10685-x
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