Early Initiation of Temozolomide Therapy May Improve Response in Aggressive Pituitary Adenomas

Early Initiation of Temozolomide Therapy May Improve Response in Aggressive Pituitary Adenomas

IntroductionAggressive pituitary adenomas (APAs) are, by definition, resistant to optimal multimodality therapy. The challenge lies in their early recognition and timely management. Temozolomide is increasingly being used in patients with APAs, but evidence supporting a favorable response with early...

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Bibliographic Details
Main Authors: Liza Das, Nidhi Gupta, Pinaki Dutta, Rama Walia, Kim Vaiphei, Ashutosh Rai, Bishan Dass Radotra, Kirti Gupta, Sreejesh Sreedharanunni, Chirag Kamal Ahuja, Anil Bhansali, Manjul Tripathi, Ridhi Sood, Sivashanmugam Dhandapani
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Endocrinology
Subjects:
temozolomide
aggressive pituitary adenomas
MGMT
controlled disease
early therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.774686/full

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