The RENAISSANCE (AIO-FLOT5) trial: effect of chemotherapy alone vs. chemotherapy followed by surgical resection on survival and quality of life in patients with limited-metastatic adenocarcinoma of the stomach or esophagogastric junction – a phase III trial of the German AIO/CAO-V/CAOGI

The RENAISSANCE (AIO-FLOT5) trial: effect of chemotherapy alone vs. chemotherapy followed by surgical resection on survival and quality of life in patients with limited-metastatic adenocarcinoma of the stomach or esophagogastric junction – a phase III trial of the German AIO/CAO-V/CAOGI

Abstract Background Historical data indicate that surgical resection may benefit select patients with metastatic gastric and gastroesophageal junction cancer. However, randomized clinical trials are lacking. The current RENAISSANCE trial addresses the potential benefits of surgical intervention in g...

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Bibliographic Details
Main Authors: Salah-Eddin Al-Batran, Thorsten O. Goetze, Daniel W. Mueller, Arndt Vogel, Michael Winkler, Sylvie Lorenzen, Alexander Novotny, Claudia Pauligk, Nils Homann, Thomas Jungbluth, Christoph Reissfelder, Karel Caca, Steffen Retter, Eva Horndasch, Julia Gumpp, Claus Bolling, Karl-Hermann Fuchs, Wolfgang Blau, Winfried Padberg, Michael Pohl, Andreas Wunsch, Patrick Michl, Frank Mannes, Matthias Schwarzbach, Harald Schmalenberg, Michael Hohaus, Christian Scholz, Christoph Benckert, Jorge Riera Knorrenschild, Veit Kanngießer, Thomas Zander, Hakan Alakus, Ralf-Dieter Hofheinz, Claus Roedel, Manish A. Shah, Mitsuru Sasako, Dietmar Lorenz, Jakob Izbicki, Wolf O. Bechstein, Hauke Lang, Stefan P. Moenig
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Cancer
Subjects:
Oligometastatic cancer
Metastatic gastric cancer
Metastatic gastroesophageal junction cancer
Limited-metastatic disease
Localized peritoneal carcinomatosis
Perioperative chemotherapy
Online Access:http://link.springer.com/article/10.1186/s12885-017-3918-9

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