A Comparison of Gallbladder Contraction Index in Diabetics and Non diabetics using Ultrasonogram: A Cross-sectional Study
Introduction: In India, the prevalence of gallstones is considered as a major public health problem and among diabetic patients the prevalence is still more increasing. Presence of Diabetic Autonomic Neuropathy (DAN) is a triggering factor for gallbladder diseases among diabetic patients. Aim:...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Pvt. Ltd.
2021-07-01
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| Series: | International Journal of Anatomy Radiology and Surgery |
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| Online Access: | http://www.ijars.net/articles/PDF/2654/48226_CE[Ra1]_F(SHU)_PF1(AKA_SHU)_PFA(AKA_KM)_PN(KM).pdf |
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| author | KP Dhivya V Malathi M Deepak S Senthilnathan R Narmadha R Shankar |
| author_facet | KP Dhivya V Malathi M Deepak S Senthilnathan R Narmadha R Shankar |
| author_sort | KP Dhivya |
| collection | DOAJ |
| description | Introduction: In India, the prevalence of gallstones is considered
as a major public health problem and among diabetic patients
the prevalence is still more increasing. Presence of Diabetic
Autonomic Neuropathy (DAN) is a triggering factor for gallbladder
diseases among diabetic patients.
Aim: To compare the gallbladder volume and contraction index
between diabetic patients and non diabetic healthy controls.
Materials and Methods: A cross-sectional study was
conducted in a tertiary care hospital at Chennai for a period
of six months from June 2019 to December 2019. The total
90 subjects were divided into two groups of 45 each, group A
consist of 45 known Type I or Type II diabetes mellitus (DM)and
group B with 45 non diabetic healthy controls. The gallbladder
volume was assessed initially in the fasting state, then the
patient was asked to have fatty meal and again the gallbladder
volume was measured after two hours for all the patients
and the gallbladder contraction index was calculated using
these values. Autonomic neuropathy grading was done after
performing neuropathy assessment tests and the association
between the gallbladder contraction index and grading of
autonomic neuropathy was analysed.
Results: The mean fasting and postprandial gallbladder volume
were much higher among diabetic patients compared to non
diabetic controls and similarly the gallbladder contraction index
was lesser among diabetic patients compared to the controls
(16.6±5.9 cm3
, 4.03±1.8 cm3
) and (32.08±11.7 cm3
, 17.4±10.6
cm3
) the difference was found to be statistically significant
(p-value<0.001). The grading of autonomic neuropathy was
inversely proportional to gallbladder contraction index and it
was found to be statistically significant (p-value<0.001).
Conclusion: The gallbladder volume was high and the
contraction index was less among the diabetic patients with
neuropathy compared to non diabetic patients and so a regular
screening for gallbladder using ultrasonogram is recommended
for long standing diabetic patients with neuropathy. |
| first_indexed | 2024-12-13T19:45:16Z |
| format | Article |
| id | doaj.art-5dc725fff16e43129bec7246b0091236 |
| institution | Directory Open Access Journal |
| issn | 2277-8543 2455-6874 |
| language | English |
| last_indexed | 2024-12-13T19:45:16Z |
| publishDate | 2021-07-01 |
| publisher | JCDR Research and Publications Pvt. Ltd. |
| record_format | Article |
| series | International Journal of Anatomy Radiology and Surgery |
| spelling | doaj.art-5dc725fff16e43129bec7246b00912362022-12-21T23:33:34ZengJCDR Research and Publications Pvt. Ltd.International Journal of Anatomy Radiology and Surgery2277-85432455-68742021-07-01103RO01RO0410.7860/IJARS/2021/48226:2654A Comparison of Gallbladder Contraction Index in Diabetics and Non diabetics using Ultrasonogram: A Cross-sectional StudyKP Dhivya0V Malathi1M Deepak2S Senthilnathan3R Narmadha4R Shankar5Senior Resident, Department of Radiology, Annapoorana Medical College and Hospital Salem, Salem, Tamil Nadu, India.Consultant Radiologist, Department of Radiology, Billroth Hospital, Chennai, Tamil Nadu, India.Assistant Professor, Department of Radiology, Annapoorana Medical College and Hospital Salem, Salem, Tamil Nadu, India.Associate Professor, Department of Radiology, Annapoorana Medical College and Hospital Salem, Salem, Tamil Nadu, India.Senior Resident, Department of Radiology, Government Mohan Kumaramangalam Medical College and Hospital Salem, Salem, Tamil Nadu, India.Professor, Preventive Medicine, VMKVMCH Salem, Salem, Tamil Nadu, India.Introduction: In India, the prevalence of gallstones is considered as a major public health problem and among diabetic patients the prevalence is still more increasing. Presence of Diabetic Autonomic Neuropathy (DAN) is a triggering factor for gallbladder diseases among diabetic patients. Aim: To compare the gallbladder volume and contraction index between diabetic patients and non diabetic healthy controls. Materials and Methods: A cross-sectional study was conducted in a tertiary care hospital at Chennai for a period of six months from June 2019 to December 2019. The total 90 subjects were divided into two groups of 45 each, group A consist of 45 known Type I or Type II diabetes mellitus (DM)and group B with 45 non diabetic healthy controls. The gallbladder volume was assessed initially in the fasting state, then the patient was asked to have fatty meal and again the gallbladder volume was measured after two hours for all the patients and the gallbladder contraction index was calculated using these values. Autonomic neuropathy grading was done after performing neuropathy assessment tests and the association between the gallbladder contraction index and grading of autonomic neuropathy was analysed. Results: The mean fasting and postprandial gallbladder volume were much higher among diabetic patients compared to non diabetic controls and similarly the gallbladder contraction index was lesser among diabetic patients compared to the controls (16.6±5.9 cm3 , 4.03±1.8 cm3 ) and (32.08±11.7 cm3 , 17.4±10.6 cm3 ) the difference was found to be statistically significant (p-value<0.001). The grading of autonomic neuropathy was inversely proportional to gallbladder contraction index and it was found to be statistically significant (p-value<0.001). Conclusion: The gallbladder volume was high and the contraction index was less among the diabetic patients with neuropathy compared to non diabetic patients and so a regular screening for gallbladder using ultrasonogram is recommended for long standing diabetic patients with neuropathy.http://www.ijars.net/articles/PDF/2654/48226_CE[Ra1]_F(SHU)_PF1(AKA_SHU)_PFA(AKA_KM)_PN(KM).pdfdiabetic autonomic neuropathydiabetes mellitusgallbladder volumegallstones |
| spellingShingle | KP Dhivya V Malathi M Deepak S Senthilnathan R Narmadha R Shankar A Comparison of Gallbladder Contraction Index in Diabetics and Non diabetics using Ultrasonogram: A Cross-sectional Study International Journal of Anatomy Radiology and Surgery diabetic autonomic neuropathy diabetes mellitus gallbladder volume gallstones |
| title | A Comparison of Gallbladder Contraction Index in Diabetics and Non diabetics using Ultrasonogram: A Cross-sectional Study |
| title_full | A Comparison of Gallbladder Contraction Index in Diabetics and Non diabetics using Ultrasonogram: A Cross-sectional Study |
| title_fullStr | A Comparison of Gallbladder Contraction Index in Diabetics and Non diabetics using Ultrasonogram: A Cross-sectional Study |
| title_full_unstemmed | A Comparison of Gallbladder Contraction Index in Diabetics and Non diabetics using Ultrasonogram: A Cross-sectional Study |
| title_short | A Comparison of Gallbladder Contraction Index in Diabetics and Non diabetics using Ultrasonogram: A Cross-sectional Study |
| title_sort | comparison of gallbladder contraction index in diabetics and non diabetics using ultrasonogram a cross sectional study |
| topic | diabetic autonomic neuropathy diabetes mellitus gallbladder volume gallstones |
| url | http://www.ijars.net/articles/PDF/2654/48226_CE[Ra1]_F(SHU)_PF1(AKA_SHU)_PFA(AKA_KM)_PN(KM).pdf |
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