Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis

Introduction: Worldwide, tuberculosis is the leading cause of death from an infectious disease. Ocular involvement can cause significant and permanent vision loss. Ocular manifestations of tuberculosis often present with visual symptoms. Asymptomatic ocular tuberculosis is uncommon and yet can have...

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Main Authors: Christopher Bartimote, Samantha Fraser-Bell, Hamish Dunn
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Respiratory Medicine Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213007121001180
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author Christopher Bartimote
Samantha Fraser-Bell
Hamish Dunn
author_facet Christopher Bartimote
Samantha Fraser-Bell
Hamish Dunn
author_sort Christopher Bartimote
collection DOAJ
description Introduction: Worldwide, tuberculosis is the leading cause of death from an infectious disease. Ocular involvement can cause significant and permanent vision loss. Ocular manifestations of tuberculosis often present with visual symptoms. Asymptomatic ocular tuberculosis is uncommon and yet can have serious consequences if missed. Case report: An immunocompetent 26-year-old Filipino man living in regional Australia who was diagnosed with active pulmonary tuberculosis and started on antitubercular therapy. He was referred to an ophthalmologist for baseline ethambutol screening to exclude pre-existing optic neuropathy. Despite having no visual symptoms, when examined, the patient had vision threatening occlusive retinal vasculitis. He was initially commenced on localised therapy via bevacizumab intravitreal injections and retinal photocoagulation. Following completion of antitubercular therapy, high dose prednisone was commenced and slowly tapered. Conclusions: We present the case of an asymptomatic sight threatening occlusive vasculitis that was discovered on pre-treatment ophthalmology review. This case emphasises the need for referral for full ophthalmic screening in newly diagnosed tuberculosis to exclude vision-threatening complications.
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spelling doaj.art-5dc88b1926e745749a44a0125d4a7b242022-12-21T22:05:34ZengElsevierRespiratory Medicine Case Reports2213-00712021-01-0133101456Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosisChristopher Bartimote0Samantha Fraser-Bell1Hamish Dunn2Ophthalmology, Royal North Shore Hospital, Sydney, Australia; The University of Sydney, Sydney, Australia; Corresponding author. Royal North Shore Hospital, Reserve Rd, St Leonards, NSW, Australia.Ophthalmology, Royal North Shore Hospital, Sydney, Australia; Ophthalmology, Sydney Eye Hospital, Sydney, Australia; The University of Sydney, Sydney, AustraliaPort Macquarie Eye Centre, Port Macquarie, Australia; The University of Sydney, Sydney, AustraliaIntroduction: Worldwide, tuberculosis is the leading cause of death from an infectious disease. Ocular involvement can cause significant and permanent vision loss. Ocular manifestations of tuberculosis often present with visual symptoms. Asymptomatic ocular tuberculosis is uncommon and yet can have serious consequences if missed. Case report: An immunocompetent 26-year-old Filipino man living in regional Australia who was diagnosed with active pulmonary tuberculosis and started on antitubercular therapy. He was referred to an ophthalmologist for baseline ethambutol screening to exclude pre-existing optic neuropathy. Despite having no visual symptoms, when examined, the patient had vision threatening occlusive retinal vasculitis. He was initially commenced on localised therapy via bevacizumab intravitreal injections and retinal photocoagulation. Following completion of antitubercular therapy, high dose prednisone was commenced and slowly tapered. Conclusions: We present the case of an asymptomatic sight threatening occlusive vasculitis that was discovered on pre-treatment ophthalmology review. This case emphasises the need for referral for full ophthalmic screening in newly diagnosed tuberculosis to exclude vision-threatening complications.http://www.sciencedirect.com/science/article/pii/S2213007121001180TuberculosisVasculitisRetinaOphthalmology
spellingShingle Christopher Bartimote
Samantha Fraser-Bell
Hamish Dunn
Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis
Respiratory Medicine Case Reports
Tuberculosis
Vasculitis
Retina
Ophthalmology
title Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis
title_full Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis
title_fullStr Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis
title_full_unstemmed Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis
title_short Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis
title_sort asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis
topic Tuberculosis
Vasculitis
Retina
Ophthalmology
url http://www.sciencedirect.com/science/article/pii/S2213007121001180
work_keys_str_mv AT christopherbartimote asymptomaticocclusiveretinalvasculitisinnewlydiagnosedactivetuberculosis
AT samanthafraserbell asymptomaticocclusiveretinalvasculitisinnewlydiagnosedactivetuberculosis
AT hamishdunn asymptomaticocclusiveretinalvasculitisinnewlydiagnosedactivetuberculosis