The value of cognitive behavioral therapy on quality of life in addition to pharmacotherapy in adults with ADHD

Introduction Treatment options for ADHD in adults consist of psycho-education, cognitive behavioral therapy (CBT), pharmacotherapy or a combination thereof. Current studies do not yet provide insights into the additive effects of CBT and pharmacotherapy regarding the quality of life in adults with...

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Main Authors: R. Wettstein, Y. Klabbers, E. Romijn, J. Nieuwveen, H. Kroesen, K. Wettstein, G. Dumont
Format: Article
Language:English
Published: Cambridge University Press 2022-06-01
Series:European Psychiatry
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S0924933822015644/type/journal_article
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author R. Wettstein
Y. Klabbers
E. Romijn
J. Nieuwveen
H. Kroesen
K. Wettstein
G. Dumont
author_facet R. Wettstein
Y. Klabbers
E. Romijn
J. Nieuwveen
H. Kroesen
K. Wettstein
G. Dumont
author_sort R. Wettstein
collection DOAJ
description Introduction Treatment options for ADHD in adults consist of psycho-education, cognitive behavioral therapy (CBT), pharmacotherapy or a combination thereof. Current studies do not yet provide insights into the additive effects of CBT and pharmacotherapy regarding the quality of life in adults with ADHD. Objectives In this study, we investigated the effect of CBT combined with pharmacotherapy on the quality of life in adults with ADHD compared to pharmacotherapy alone. Methods In this multicenter prospective cohort study a total of 627 patients were included, 305 where included in the pharmacotherapy only group and 322 in de combination group (CBT and pharmacotherapy). The Adult ADHD Quality-of-Life scale (AAQoL) was conducted at baseline and at the end of treatment. Results No significant differences were found in gender or age between groups at baseline. The average improvement in the AAQoL total score in the pharmacotherapy group was 26.81(17.12) and in the combination group 25.45(16.33) and showed no significant difference (t(543) = 0.96, p = 0.34). At baseline the average total score in the pharmacotherapy group was 45.5(12.37) and 42.22(12.73) in the combination group (t(543)=2.86, p = 0.004). The average total score at the end of treatment in the pharmacotherapy and combination group was 72.31(12.99) and 67.67(12.45), respectively (t(543)=426, p <0.001). Conclusions To our knowledge, this is the first study to describe the value of CBT in addition to pharmacotherapy on the quality of life in adults with ADHD. Contrary to our expectations, there was no significant effect of CBT in addition to pharmacotherapy on the quality of life. Disclosure No significant relationships.
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spelling doaj.art-5dc8fa17ef1448c3a2b4f8c92bb319fc2023-11-17T05:06:53ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S610S61110.1192/j.eurpsy.2022.1564The value of cognitive behavioral therapy on quality of life in addition to pharmacotherapy in adults with ADHDR. Wettstein0Y. Klabbers1E. Romijn2J. Nieuwveen3H. Kroesen4K. Wettstein5G. Dumont6Amsterdam university medical center, Clinical Pharmacology And Pharmacy, Amsterdam, Netherlands ADHDcentraal, Research & Development, Nieuwegein, NetherlandsGGNet, Ivb, Warnsveld, NetherlandsADHDcentraal, Research & Development, Nieuwegein, NetherlandsADHDcentraal, Research & Development, Nieuwegein, NetherlandsADHDcentraal, Research & Development, Nieuwegein, NetherlandsADHDcentraal, Research & Development, Nieuwegein, NetherlandsAmsterdam university medical center, Clinical Pharmacology And Pharmacy, Amsterdam, Netherlands ADHDcentraal, Research & Development, Nieuwegein, Netherlands Introduction Treatment options for ADHD in adults consist of psycho-education, cognitive behavioral therapy (CBT), pharmacotherapy or a combination thereof. Current studies do not yet provide insights into the additive effects of CBT and pharmacotherapy regarding the quality of life in adults with ADHD. Objectives In this study, we investigated the effect of CBT combined with pharmacotherapy on the quality of life in adults with ADHD compared to pharmacotherapy alone. Methods In this multicenter prospective cohort study a total of 627 patients were included, 305 where included in the pharmacotherapy only group and 322 in de combination group (CBT and pharmacotherapy). The Adult ADHD Quality-of-Life scale (AAQoL) was conducted at baseline and at the end of treatment. Results No significant differences were found in gender or age between groups at baseline. The average improvement in the AAQoL total score in the pharmacotherapy group was 26.81(17.12) and in the combination group 25.45(16.33) and showed no significant difference (t(543) = 0.96, p = 0.34). At baseline the average total score in the pharmacotherapy group was 45.5(12.37) and 42.22(12.73) in the combination group (t(543)=2.86, p = 0.004). The average total score at the end of treatment in the pharmacotherapy and combination group was 72.31(12.99) and 67.67(12.45), respectively (t(543)=426, p <0.001). Conclusions To our knowledge, this is the first study to describe the value of CBT in addition to pharmacotherapy on the quality of life in adults with ADHD. Contrary to our expectations, there was no significant effect of CBT in addition to pharmacotherapy on the quality of life. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933822015644/type/journal_articleCognitive behavioral therapyQuality of Lifeadultsadhd
spellingShingle R. Wettstein
Y. Klabbers
E. Romijn
J. Nieuwveen
H. Kroesen
K. Wettstein
G. Dumont
The value of cognitive behavioral therapy on quality of life in addition to pharmacotherapy in adults with ADHD
European Psychiatry
Cognitive behavioral therapy
Quality of Life
adults
adhd
title The value of cognitive behavioral therapy on quality of life in addition to pharmacotherapy in adults with ADHD
title_full The value of cognitive behavioral therapy on quality of life in addition to pharmacotherapy in adults with ADHD
title_fullStr The value of cognitive behavioral therapy on quality of life in addition to pharmacotherapy in adults with ADHD
title_full_unstemmed The value of cognitive behavioral therapy on quality of life in addition to pharmacotherapy in adults with ADHD
title_short The value of cognitive behavioral therapy on quality of life in addition to pharmacotherapy in adults with ADHD
title_sort value of cognitive behavioral therapy on quality of life in addition to pharmacotherapy in adults with adhd
topic Cognitive behavioral therapy
Quality of Life
adults
adhd
url https://www.cambridge.org/core/product/identifier/S0924933822015644/type/journal_article
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