A Metal-Containing NP Approach to Treat Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA): Prospects and Challenges

Methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) is an important cause of pneumonia in humans, and it is associated with high morbidity and mortality rates, especially in immunocompromised patients. Its high rate of multidrug resistance led to an exploration of novel antimicrobi...

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Bibliographic Details
Main Authors: Wendy Wai Yeng Yeo, Sathiya Maran, Amanda Shen-Yee Kong, Wan-Hee Cheng, Swee-Hua Erin Lim, Jiun-Yan Loh, Kok-Song Lai
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/15/17/5802
Description
Summary:Methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) is an important cause of pneumonia in humans, and it is associated with high morbidity and mortality rates, especially in immunocompromised patients. Its high rate of multidrug resistance led to an exploration of novel antimicrobials. Metal nanoparticles have shown potent antibacterial activity, thus instigating their application in MRSA. This review summarizes current insights of Metal-Containing NPs in treating MRSA. This review also provides an in-depth appraisal of opportunities and challenges in utilizing metal-NPs to treat MRSA.
ISSN:1996-1944