Metabolic phenotyping of the human microbiome [version 1; peer review: 2 approved]
The human microbiome has been identified as having a key role in health and numerous diseases. Trillions of microbial cells and viral particles comprise the microbiome, each representing modifiable working elements of an intricate bioactive ecosystem. The significance of the human microbiome as it r...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2019-11-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/8-1956/v1 |
| _version_ | 1818146426969915392 |
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| author | Wiley Barton Orla O'Sullivan Paul D. Cotter |
| author_facet | Wiley Barton Orla O'Sullivan Paul D. Cotter |
| author_sort | Wiley Barton |
| collection | DOAJ |
| description | The human microbiome has been identified as having a key role in health and numerous diseases. Trillions of microbial cells and viral particles comprise the microbiome, each representing modifiable working elements of an intricate bioactive ecosystem. The significance of the human microbiome as it relates to human biology has progressed through culture-dependent (for example, media-based methods) and, more recently, molecular (for example, genetic sequencing and metabolomic analysis) techniques. The latter have become increasingly popular and evolved from being used for taxonomic identification of microbiota to elucidation of functional capacity (sequencing) and metabolic activity (metabolomics). This review summarises key elements of the human microbiome and its metabolic capabilities within the context of health and disease. |
| first_indexed | 2024-12-11T12:19:10Z |
| format | Article |
| id | doaj.art-5dccf9b811924eee88b1393d790a1f9b |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-12-11T12:19:10Z |
| publishDate | 2019-11-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-5dccf9b811924eee88b1393d790a1f9b2022-12-22T01:07:34ZengF1000 Research LtdF1000Research2046-14022019-11-01810.12688/f1000research.19481.121360Metabolic phenotyping of the human microbiome [version 1; peer review: 2 approved]Wiley Barton0Orla O'Sullivan1Paul D. Cotter2APC Microbiome Ireland, University College Cork, National University of Ireland, Cork, T12YT20, IrelandAPC Microbiome Ireland, University College Cork, National University of Ireland, Cork, T12YT20, IrelandAPC Microbiome Ireland, University College Cork, National University of Ireland, Cork, T12YT20, IrelandThe human microbiome has been identified as having a key role in health and numerous diseases. Trillions of microbial cells and viral particles comprise the microbiome, each representing modifiable working elements of an intricate bioactive ecosystem. The significance of the human microbiome as it relates to human biology has progressed through culture-dependent (for example, media-based methods) and, more recently, molecular (for example, genetic sequencing and metabolomic analysis) techniques. The latter have become increasingly popular and evolved from being used for taxonomic identification of microbiota to elucidation of functional capacity (sequencing) and metabolic activity (metabolomics). This review summarises key elements of the human microbiome and its metabolic capabilities within the context of health and disease.https://f1000research.com/articles/8-1956/v1 |
| spellingShingle | Wiley Barton Orla O'Sullivan Paul D. Cotter Metabolic phenotyping of the human microbiome [version 1; peer review: 2 approved] F1000Research |
| title | Metabolic phenotyping of the human microbiome [version 1; peer review: 2 approved] |
| title_full | Metabolic phenotyping of the human microbiome [version 1; peer review: 2 approved] |
| title_fullStr | Metabolic phenotyping of the human microbiome [version 1; peer review: 2 approved] |
| title_full_unstemmed | Metabolic phenotyping of the human microbiome [version 1; peer review: 2 approved] |
| title_short | Metabolic phenotyping of the human microbiome [version 1; peer review: 2 approved] |
| title_sort | metabolic phenotyping of the human microbiome version 1 peer review 2 approved |
| url | https://f1000research.com/articles/8-1956/v1 |
| work_keys_str_mv | AT wileybarton metabolicphenotypingofthehumanmicrobiomeversion1peerreview2approved AT orlaosullivan metabolicphenotypingofthehumanmicrobiomeversion1peerreview2approved AT pauldcotter metabolicphenotypingofthehumanmicrobiomeversion1peerreview2approved |