VMAT2 availability in Parkinson’s disease with probable REM sleep behaviour disorder

VMAT2 availability in Parkinson’s disease with probable REM sleep behaviour disorder

Abstract REM sleep behaviour disorder (RBD) can be an early non-motor symptom of Parkinson’s disease (PD) with pathology involving mainly the pontine nuclei. Beyond the brainstem, it is unclear if RBD patients comorbid with PD have more affected striatal dopamine denervation compared to PD patients...

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Bibliographic Details
Main Authors: Mikaeel Valli, Sang Soo Cho, Carme Uribe, Mario Masellis, Robert Chen, Alexander Mihaescu, Antonio P. Strafella
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Molecular Brain
Subjects:
Parkinson’s disease
REM sleep behaviour disorder
Positron emission tomography
VMAT2
[11C]DTBZ
Online Access:https://doi.org/10.1186/s13041-021-00875-7

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