Game Birds Can Act as Intermediaries of Virulent Genotype VII Avian Orthoavulavirus-1 between Wild Birds and Domestic Poultry
Newcastle Disease (ND), caused by virulent forms of Avian orthoavulavirus serotype-1 (AOAV-1) is an economically important avian disease worldwide. The past two incursions of ND into the United Kingdom occurred in game bird populations during 2005 and 2006. The nature of the game bird semi-feral rea...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/15/2/536 |
| _version_ | 1797617783764156416 |
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| author | Craig S. Ross Paul Skinner David Sutton Jo Mayers Alex Nunez Sharon M. Brookes Ashley C. Banyard Ian H. Brown |
| author_facet | Craig S. Ross Paul Skinner David Sutton Jo Mayers Alex Nunez Sharon M. Brookes Ashley C. Banyard Ian H. Brown |
| author_sort | Craig S. Ross |
| collection | DOAJ |
| description | Newcastle Disease (ND), caused by virulent forms of Avian orthoavulavirus serotype-1 (AOAV-1) is an economically important avian disease worldwide. The past two incursions of ND into the United Kingdom occurred in game bird populations during 2005 and 2006. The nature of the game bird semi-feral rearing system, which can bring these birds into close contact with both wild birds and commercial or backyard poultry, has been hypothesized to act as a bridge between these two environments. As such, the risk that AOAV-1-infected game birds may pose to the UK poultry industry was investigated. Pheasants, partridges and chickens were experimentally infected with the virulent strain APMV-1/Chicken/Bulgaria/112/13, a genotype VII.2 virus associated with ND outbreaks in Eastern Europe. The study demonstrated that both chickens and pheasants are susceptible to infection with APMV-1/Chicken/Bulgaria/112/13, which results in high mortality and onward transmission. Partridges by contrast are susceptible to infection, but mortality was reduced, as was onward transmission. However, the data indicated that both pheasants and partridges may serve as intermediate hosts of AOAV-1 and may bridge the wild bird–domestic poultry interface enabling transmission into an economically damaging environment where morbidity and mortality may be high. |
| first_indexed | 2024-03-11T08:00:40Z |
| format | Article |
| id | doaj.art-5dcd5a5c3f5849b88aaa068c6488ba9a |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-11T08:00:40Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-5dcd5a5c3f5849b88aaa068c6488ba9a2023-11-16T23:50:21ZengMDPI AGViruses1999-49152023-02-0115253610.3390/v15020536Game Birds Can Act as Intermediaries of Virulent Genotype VII Avian Orthoavulavirus-1 between Wild Birds and Domestic PoultryCraig S. Ross0Paul Skinner1David Sutton2Jo Mayers3Alex Nunez4Sharon M. Brookes5Ashley C. Banyard6Ian H. Brown7Animal and Plant Health Agency (APHA), Woodham Lane, Addlestone KT15 3NB, UKAnimal and Plant Health Agency (APHA), Woodham Lane, Addlestone KT15 3NB, UKAnimal and Plant Health Agency (APHA), Woodham Lane, Addlestone KT15 3NB, UKAnimal and Plant Health Agency (APHA), Woodham Lane, Addlestone KT15 3NB, UKAnimal and Plant Health Agency (APHA), Woodham Lane, Addlestone KT15 3NB, UKAnimal and Plant Health Agency (APHA), Woodham Lane, Addlestone KT15 3NB, UKAnimal and Plant Health Agency (APHA), Woodham Lane, Addlestone KT15 3NB, UKAnimal and Plant Health Agency (APHA), Woodham Lane, Addlestone KT15 3NB, UKNewcastle Disease (ND), caused by virulent forms of Avian orthoavulavirus serotype-1 (AOAV-1) is an economically important avian disease worldwide. The past two incursions of ND into the United Kingdom occurred in game bird populations during 2005 and 2006. The nature of the game bird semi-feral rearing system, which can bring these birds into close contact with both wild birds and commercial or backyard poultry, has been hypothesized to act as a bridge between these two environments. As such, the risk that AOAV-1-infected game birds may pose to the UK poultry industry was investigated. Pheasants, partridges and chickens were experimentally infected with the virulent strain APMV-1/Chicken/Bulgaria/112/13, a genotype VII.2 virus associated with ND outbreaks in Eastern Europe. The study demonstrated that both chickens and pheasants are susceptible to infection with APMV-1/Chicken/Bulgaria/112/13, which results in high mortality and onward transmission. Partridges by contrast are susceptible to infection, but mortality was reduced, as was onward transmission. However, the data indicated that both pheasants and partridges may serve as intermediate hosts of AOAV-1 and may bridge the wild bird–domestic poultry interface enabling transmission into an economically damaging environment where morbidity and mortality may be high.https://www.mdpi.com/1999-4915/15/2/536Avian orthoavulavirus-1AOAV-1Newcastle diseaseNDVgame birdspoultry |
| spellingShingle | Craig S. Ross Paul Skinner David Sutton Jo Mayers Alex Nunez Sharon M. Brookes Ashley C. Banyard Ian H. Brown Game Birds Can Act as Intermediaries of Virulent Genotype VII Avian Orthoavulavirus-1 between Wild Birds and Domestic Poultry Viruses Avian orthoavulavirus-1 AOAV-1 Newcastle disease NDV game birds poultry |
| title | Game Birds Can Act as Intermediaries of Virulent Genotype VII Avian Orthoavulavirus-1 between Wild Birds and Domestic Poultry |
| title_full | Game Birds Can Act as Intermediaries of Virulent Genotype VII Avian Orthoavulavirus-1 between Wild Birds and Domestic Poultry |
| title_fullStr | Game Birds Can Act as Intermediaries of Virulent Genotype VII Avian Orthoavulavirus-1 between Wild Birds and Domestic Poultry |
| title_full_unstemmed | Game Birds Can Act as Intermediaries of Virulent Genotype VII Avian Orthoavulavirus-1 between Wild Birds and Domestic Poultry |
| title_short | Game Birds Can Act as Intermediaries of Virulent Genotype VII Avian Orthoavulavirus-1 between Wild Birds and Domestic Poultry |
| title_sort | game birds can act as intermediaries of virulent genotype vii avian orthoavulavirus 1 between wild birds and domestic poultry |
| topic | Avian orthoavulavirus-1 AOAV-1 Newcastle disease NDV game birds poultry |
| url | https://www.mdpi.com/1999-4915/15/2/536 |
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