Small bowel capsule endoscopy and portal hypertensive enteropathy in cirrhotic patients: results from a tertiary referral centre
Background and rationale. Portal hypertensive enteropathy (PHE) remains difficult to diagnose in patients with cirrhosis and portal hypertension. Limited test choices exist for the inspection of the small bowel in these patients. Small bowel capsule endoscopy (SBCE) is ideal in this situation but ra...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-05-01
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| Series: | Annals of Hepatology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268119306581 |
| _version_ | 1818588194469314560 |
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| author | Konstantinos J. Dabos Diana E. Yung Leonidas Bartzis Peter C. Hayes John N. Plevris Anastasios Koulaouzidis |
| author_facet | Konstantinos J. Dabos Diana E. Yung Leonidas Bartzis Peter C. Hayes John N. Plevris Anastasios Koulaouzidis |
| author_sort | Konstantinos J. Dabos |
| collection | DOAJ |
| description | Background and rationale. Portal hypertensive enteropathy (PHE) remains difficult to diagnose in patients with cirrhosis and portal hypertension. Limited test choices exist for the inspection of the small bowel in these patients. Small bowel capsule endoscopy (SBCE) is ideal in this situation but rarely performed. We aimed to determine the prevalence of PHE using SBCE in a cirrhotic patient population and correlate its presence with clinical and CT imaging findings.Material and methods. We retrospectively analysed data from cirrhotic patients who underwent SBCE at our unit. Studies were evaluated for the presence of cirrhosis-related findings in the oesophagus, stomach and small-bowel. The relationships between PHE and patients’ clinical characteristics were evaluated.Results. 53 patients with cirrhosis underwent SCBE. We used PillCam®SB on 36 patients and MiroCam® capsule on 17. Thirty patients were referred for iron deficiency anaemia, 15 for obscure gastrointestinal bleeding, and 4 for other indications. Four data sets were not available for review, leaving 49 patients. Mean age was 61.19 ± 14.54 years (M/F = 27/22). Six SBCE examinations were incomplete. Thirty three patients had evidence of portal hypertensive gastropathy (PHG) and 17 had evidence of oesophageal varices. In total, 29 patients had SCBE evidence of PHE (57%). 28/29 (96.5%) patients with PHE had also evidence of PHG. 13/17 (76.4%) patients with oesophageal varices had also evidence of PHE.Conclusions. The prevalence of PHE in our study was 57%. SBCE is a useful tool in evaluating PHE in cirrhotic patients irrespective of aetiology. |
| first_indexed | 2024-12-16T09:20:53Z |
| format | Article |
| id | doaj.art-5dd29aea66a1415b8102fbbe75d5d3ac |
| institution | Directory Open Access Journal |
| issn | 1665-2681 |
| language | English |
| last_indexed | 2024-12-16T09:20:53Z |
| publishDate | 2016-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Annals of Hepatology |
| spelling | doaj.art-5dd29aea66a1415b8102fbbe75d5d3ac2022-12-21T22:36:46ZengElsevierAnnals of Hepatology1665-26812016-05-01153394401Small bowel capsule endoscopy and portal hypertensive enteropathy in cirrhotic patients: results from a tertiary referral centreKonstantinos J. Dabos0Diana E. Yung1Leonidas Bartzis2Peter C. Hayes3John N. Plevris4Anastasios Koulaouzidis5Centre of Liver and Digestive Disorders, Royal Infirmary of Edinburgh. Edinburgh, United KingdomCorrespondence a reprint request:; Centre of Liver and Digestive Disorders, Royal Infirmary of Edinburgh. Edinburgh, United KingdomCentre of Liver and Digestive Disorders, Royal Infirmary of Edinburgh. Edinburgh, United KingdomCentre of Liver and Digestive Disorders, Royal Infirmary of Edinburgh. Edinburgh, United KingdomCentre of Liver and Digestive Disorders, Royal Infirmary of Edinburgh. Edinburgh, United KingdomCentre of Liver and Digestive Disorders, Royal Infirmary of Edinburgh. Edinburgh, United KingdomBackground and rationale. Portal hypertensive enteropathy (PHE) remains difficult to diagnose in patients with cirrhosis and portal hypertension. Limited test choices exist for the inspection of the small bowel in these patients. Small bowel capsule endoscopy (SBCE) is ideal in this situation but rarely performed. We aimed to determine the prevalence of PHE using SBCE in a cirrhotic patient population and correlate its presence with clinical and CT imaging findings.Material and methods. We retrospectively analysed data from cirrhotic patients who underwent SBCE at our unit. Studies were evaluated for the presence of cirrhosis-related findings in the oesophagus, stomach and small-bowel. The relationships between PHE and patients’ clinical characteristics were evaluated.Results. 53 patients with cirrhosis underwent SCBE. We used PillCam®SB on 36 patients and MiroCam® capsule on 17. Thirty patients were referred for iron deficiency anaemia, 15 for obscure gastrointestinal bleeding, and 4 for other indications. Four data sets were not available for review, leaving 49 patients. Mean age was 61.19 ± 14.54 years (M/F = 27/22). Six SBCE examinations were incomplete. Thirty three patients had evidence of portal hypertensive gastropathy (PHG) and 17 had evidence of oesophageal varices. In total, 29 patients had SCBE evidence of PHE (57%). 28/29 (96.5%) patients with PHE had also evidence of PHG. 13/17 (76.4%) patients with oesophageal varices had also evidence of PHE.Conclusions. The prevalence of PHE in our study was 57%. SBCE is a useful tool in evaluating PHE in cirrhotic patients irrespective of aetiology.http://www.sciencedirect.com/science/article/pii/S1665268119306581Capsule endoscopySmall-bowelPortal hypertensionEnteropathy-VaricesCirrhosisObscure GI bleeding |
| spellingShingle | Konstantinos J. Dabos Diana E. Yung Leonidas Bartzis Peter C. Hayes John N. Plevris Anastasios Koulaouzidis Small bowel capsule endoscopy and portal hypertensive enteropathy in cirrhotic patients: results from a tertiary referral centre Annals of Hepatology Capsule endoscopy Small-bowel Portal hypertension Enteropathy-Varices Cirrhosis Obscure GI bleeding |
| title | Small bowel capsule endoscopy and portal hypertensive enteropathy in cirrhotic patients: results from a tertiary referral centre |
| title_full | Small bowel capsule endoscopy and portal hypertensive enteropathy in cirrhotic patients: results from a tertiary referral centre |
| title_fullStr | Small bowel capsule endoscopy and portal hypertensive enteropathy in cirrhotic patients: results from a tertiary referral centre |
| title_full_unstemmed | Small bowel capsule endoscopy and portal hypertensive enteropathy in cirrhotic patients: results from a tertiary referral centre |
| title_short | Small bowel capsule endoscopy and portal hypertensive enteropathy in cirrhotic patients: results from a tertiary referral centre |
| title_sort | small bowel capsule endoscopy and portal hypertensive enteropathy in cirrhotic patients results from a tertiary referral centre |
| topic | Capsule endoscopy Small-bowel Portal hypertension Enteropathy-Varices Cirrhosis Obscure GI bleeding |
| url | http://www.sciencedirect.com/science/article/pii/S1665268119306581 |
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