Essential Regression: A generalizable framework for inferring causal latent factors from multi-omic datasets
Summary: High-dimensional cellular and molecular profiling of biological samples highlights the need for analytical approaches that can integrate multi-omic datasets to generate prioritized causal inferences. Current methods are limited by high dimensionality of the combined datasets, the difference...
Main Authors: | Xin Bing, Tyler Lovelace, Florentina Bunea, Marten Wegkamp, Sudhir Pai Kasturi, Harinder Singh, Panayiotis V. Benos, Jishnu Das |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-05-01
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Series: | Patterns |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666389922000538 |
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