p53 and telomerase control rat myocardial tissue response to hypoxia and ageing

p53 and telomerase control rat myocardial tissue response to hypoxia and ageing

Show other versions (1)

Cellular senescence implies loss of proliferative and tissue regenerative capability. Also hypoxia, producing Reactive Oxygen Species (ROS), can damage cellular components through the oxidation of DNA, proteins and lipids, thus influencing the shortening of telomeres. Since ribonucleoprotein Telomer...

Full description

Bibliographic Details
Main Authors:	A. Cataldi, S. Zara, M. Rapino, M. Zingariello, V. di Giacomo, A. Antonucci
Format:	Article
Language:	English
Published:	PAGEPress Publications 2009-12-01
Series:	European Journal of Histochemistry
Online Access:	http://www.ejh.it/index.php/ejh/article/view/1531

Similar Items

p53 and telomerase control rat myocardial tissue response to hypoxia and ageing
by: A. Antonucci, et al.
Published: (2009-12-01)

pPKCα mediated-HIF-1α activation related to the morphological modifications occurring in neonatal myocardial tissue in response to severe and mild hyperoxia
by: S. Zara, et al.
Published: (2012-01-01)

Prospects for rejuvenation of aged tissue by telomerase reactivation.
by: Cox, L, et al.
Published: (2010)

Telomeres and Telomerase in The Aging Heart
by: Anna Meiliana, et al.
Published: (2017-12-01)

Premature aging in telomerase-deficient zebrafish
by: Monique Anchelin, et al.
Published: (2013-09-01)

Role of Telomeres and Telomerase in Cancer and Aging
by: Gabriele Saretzki
Published: (2023-06-01)

The role of p53 in hypoxia-induced apoptosis
by: Poole, R
Published: (2010)

Human Telomerase RNA: Telomerase Component or More?
by: Maria Rubtsova, et al.
Published: (2020-06-01)

Special Issue: “Telomerase: Role in Health and Aging”
by: Yegor E. Yegorov
Published: (2022-11-01)

Telomeres and Telomerase in Heart Ontogenesis, Aging and Regeneration
by: Denis Nalobin, et al.
Published: (2020-02-01)

Behaviour of telomere and telomerase during aging and regeneration in zebrafish.
by: Monique Anchelin, et al.
Published: (2011-02-01)

Utility of Telomerase-pot1 Fusion Protein in Vascular Tissue Engineering
by: Thomas H. Petersen, et al.
Published: (2010-01-01)

Telomere Lengths and Telomerase Activity in Dog Tissues: A Potential Model System to Study Human Telomere and Telomerase Biology
by: Lubna Nasir, et al.
Published: (2001-01-01)

An Alternate Splicing Variant of the Human Telomerase Catalytic Subunit Inhibits Telomerase Activity
by: Xiaoming Yi, et al.
Published: (2000-09-01)

Radiolabeled oligonucleotides targeting the RNA subunit of telomerase inhibit telomerase and induce DNA damage in telomerase-positive cancer cells
by: Jackson, MR, et al.
Published: (2019)

Pulmonary Alveolar Stem Cell Senescence, Apoptosis, and Differentiation by p53-Dependent and -Independent Mechanisms in Telomerase-Deficient Mice
by: Kexiong Zhang, et al.
Published: (2021-10-01)

A telomerase em células-tronco hematopoéticas Telomerase in hematopoietic stem cells
by: Silvana Perini, et al.
Published: (2008-02-01)

Telomeres and telomerase in basal Metazoa
by: I Udroiu, et al.
Published: (2017-06-01)

TCAB1 prevents nucleolar accumulation of the telomerase RNA to facilitate telomerase assembly
by: Basma M. Klump, et al.
Published: (2023-06-01)

Oxidative Stress in Liver Tissue of Rat Induced by Chronic Systemic Hypoxia
by: Sri A. Widia A. Jusman, et al.
Published: (2010-10-01)

Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells
by: Christine A. Armstrong, et al.
Published: (2017-01-01)

Lack of telomerase reduces cancer incidence and increases lifespan of zebrafish tp53 M214K mutants
by: Naz Şerifoğlu, et al.
Published: (2024-03-01)

Telomerase activator-65 and pomegranate peel improved the health status of the liver in aged rats; multi-targets involved
by: Ameera Alshinnawy, et al.
Published: (2021-06-01)

Telomerase deficiency reflects age-associated changes in CD4+ T cells
by: Diana M. Matthe, et al.
Published: (2022-03-01)

Telomerase and Telomeres in Endometrial Cancer
by: Rafah A. A. Alnafakh, et al.
Published: (2019-05-01)

Mechanisms of nucleotide selection by telomerase
by: Matthew A Schaich, et al.
Published: (2020-06-01)

Telomerase is required for zebrafish lifespan.
by: Catarina M Henriques, et al.
Published: (2013-01-01)

Human telomerase reverse transcriptase (hTERT) Q169 is essential for telomerase function in vitro and in vivo.
by: Haley D M Wyatt, et al.
Published: (2009-09-01)

Targeting telomerase with radiolabeled inhibitors.
by: Waghorn, P, et al.
Published: (2016)

Time-dependent effect of severe hypoxia/reoxygenation on oxidative stress level, antioxidant capacity and p53 accumulation in mitochondria of rat heart
by: O. A. Gonchar, et al.
Published: (2017-12-01)

Chitlac-Coated Thermosets Enhance Osteogenesis and Angiogenesis in a Co-culture of Dental Pulp Stem Cells and Endothelial Cells
by: Monica Rapino, et al.
Published: (2019-06-01)

Telomeres and telomerase in cancer /
by: Hiyama, Keiko
Published: (2009)

Telomerase and cells youth.
by: Alexander Benavides Couto, et al.
Published: (2008-08-01)

Telomerase and cells youth.
by: Alexander Benavides Couto, et al.
Published: (2008-08-01)

Evolution of the Arabidopsis telomerase RNA
by: Mark A Beilstein, et al.
Published: (2012-09-01)

Neuroprotective and Neuromodulatory Effects Induced by Cannabidiol and Cannabigerol in Rat Hypo-E22 cells and Isolated Hypothalamus
by: Viviana di Giacomo, et al.
Published: (2020-01-01)

Human Telomerase RNA Protein Encoded by Telomerase RNA is Involved in Metabolic Responses
by: Viktoriia Shliapina, et al.
Published: (2021-12-01)

The role of telomerase and viruses interaction in cancer development, and telomerase-dependent therapeutic approaches
by: Ali Salimi-Jeda, et al.
Published: (2021-01-01)

Hypoxia Predicts Poor Prognosis in Neuroblastoma Patients and Associates with Biological Mechanisms Involved in Telomerase Activation and Tumor Microenvironment Reprogramming
by: Davide Cangelosi, et al.
Published: (2020-08-01)

A subset of gut leukocytes has telomerase-dependent “hyper-long” telomeres and require telomerase for function in zebrafish
by: Pam S. Ellis, et al.
Published: (2022-07-01)