Role of yUbp8 in Mitochondria and Hypoxia Entangles the Finding of Human Ortholog Usp22 in the Glioblastoma Pseudo-Palisade Microlayer

Role of yUbp8 in Mitochondria and Hypoxia Entangles the Finding of Human Ortholog Usp22 in the Glioblastoma Pseudo-Palisade Microlayer

KAT Gcn5 and DUB Ubp8 are required for respiration and mitochondria functions in budding yeast, and in this study we show that loss of respiratory activity is acquired over time. Interestingly, we show that absence of Ubp8 allows cells to grow in hypoxic conditions with altered mitophagy. Comparativ...

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Bibliographic Details
Main Authors: Veronica De Luca, Manuela Leo, Elisabetta Cretella, Arianna Montanari, Michele Saliola, Gabriele Ciaffi, Andrea Vecchione, Antonella Stoppacciaro, Patrizia Filetici
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
Gcn5
Ubp8
Usp22
mitochondria
hypoxia
glioblastoma
Online Access:https://www.mdpi.com/2073-4409/11/10/1682

Internet

https://www.mdpi.com/2073-4409/11/10/1682

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