Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72

Antibodies are a key resource in biomedical research yet there are no community-accepted standards to rigorously characterize their quality. Here we develop a procedure to validate pre-existing antibodies. Human cell lines with high expression of a target, determined through a proteomics database, a...

全面介紹

書目詳細資料
Main Authors: Carl Laflamme, Paul M McKeever, Rahul Kumar, Julie Schwartz, Mahshad Kolahdouzan, Carol X Chen, Zhipeng You, Faiza Benaliouad, Opher Gileadi, Heidi M McBride, Thomas M Durcan, Aled M Edwards, Luke M Healy, Janice Robertson, Peter S McPherson
格式: Article
語言:English
出版: eLife Sciences Publications Ltd 2019-10-01
叢編:eLife
主題:
在線閱讀:https://elifesciences.org/articles/48363