A Clinical Audit of Post-Operative Outcomes of Laparoscopic Nissen’s Fundoplication in a Single Center in Sub-Saharan Africa
Introduction: Gastroesophageal reflux disease (GERD) is a common benign condition with a population prevalence of 18–28%. Laparoscopic antireflux surgery is increasingly being offered to patients with GERD in our setting; however, the outcomes remain unknown. Methodology: A retrospective clinical au...
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| 格式: | 文件 |
| 语言: | English |
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Surgical Society of Kenya
2024-01-01
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| 丛编: | The Annals of African Surgery |
| 主题: | |
| 在线阅读: | https://www.annalsofafricansurgery.com/post-operative-outcomes-of-laparoscopic-nissens-fundoplication |
| _version_ | 1827385162281779200 |
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| author | Cecilia Muvenyi Munguti Bernard Ndung’u |
| author_facet | Cecilia Muvenyi Munguti Bernard Ndung’u |
| author_sort | Cecilia Muvenyi Munguti |
| collection | DOAJ |
| description | Introduction: Gastroesophageal reflux disease (GERD) is a common benign condition with a population prevalence of 18–28%. Laparoscopic antireflux surgery is increasingly being offered to patients with GERD in our setting; however, the outcomes remain unknown. Methodology: A retrospective clinical audit of patients who underwent laparoscopic Nissen’s fundoplication in a single center. Data were summarized as mean (±SD) and median (interquartile range [IQR]); associations were analyzed with Chi square or Fischer’s exact test. A Modified Visick scoring system was used to assess the severity of symptoms after surgery. Regression models were used to analyze the factors associated with recurrence. Kaplan–Meier plots were plotted, and cox regression models, hazard ratio, and their confidence intervals were calculated. Results: A total of 127 patients were identified, with 6 having had previous laparoscopic Nissen’s fundoplication. Post-operative modified Visick scores at 2 weeks and 3 months were 1.04(±0.05) and 1.03 (±0.04), respectively, for both typical and atypical symptoms. The recurrence rate was 12.6%, with 87.4% 5-year recurrence-free survival. Conclusion: Laparoscopic Nissen’s fundoplication provides good control of both typical and atypical GERD symptoms with a low recurrence rate and a 5- year recurrence-free survival that is comparable to universal rates.
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| first_indexed | 2024-03-08T15:16:10Z |
| format | Article |
| id | doaj.art-5ddbd5e8a8984583b4c99d7aae9b1e18 |
| institution | Directory Open Access Journal |
| issn | 1999-9674 2523-0816 |
| language | English |
| last_indexed | 2024-03-08T15:16:10Z |
| publishDate | 2024-01-01 |
| publisher | Surgical Society of Kenya |
| record_format | Article |
| series | The Annals of African Surgery |
| spelling | doaj.art-5ddbd5e8a8984583b4c99d7aae9b1e182024-01-10T11:51:40ZengSurgical Society of KenyaThe Annals of African Surgery1999-96742523-08162024-01-012111522http://dx.doi.org/10.4314/aas.v21i1.3A Clinical Audit of Post-Operative Outcomes of Laparoscopic Nissen’s Fundoplication in a Single Center in Sub-Saharan AfricaCecilia Muvenyi Munguti0https://orcid.org/0000-0001-7400-6446Bernard Ndung’u1https://orcid.org/0000-0001-6412-6225Mount Kenya University, Thika, KenyaUniversity of Nairobi, Nairobi, KenyaIntroduction: Gastroesophageal reflux disease (GERD) is a common benign condition with a population prevalence of 18–28%. Laparoscopic antireflux surgery is increasingly being offered to patients with GERD in our setting; however, the outcomes remain unknown. Methodology: A retrospective clinical audit of patients who underwent laparoscopic Nissen’s fundoplication in a single center. Data were summarized as mean (±SD) and median (interquartile range [IQR]); associations were analyzed with Chi square or Fischer’s exact test. A Modified Visick scoring system was used to assess the severity of symptoms after surgery. Regression models were used to analyze the factors associated with recurrence. Kaplan–Meier plots were plotted, and cox regression models, hazard ratio, and their confidence intervals were calculated. Results: A total of 127 patients were identified, with 6 having had previous laparoscopic Nissen’s fundoplication. Post-operative modified Visick scores at 2 weeks and 3 months were 1.04(±0.05) and 1.03 (±0.04), respectively, for both typical and atypical symptoms. The recurrence rate was 12.6%, with 87.4% 5-year recurrence-free survival. Conclusion: Laparoscopic Nissen’s fundoplication provides good control of both typical and atypical GERD symptoms with a low recurrence rate and a 5- year recurrence-free survival that is comparable to universal rates. https://www.annalsofafricansurgery.com/post-operative-outcomes-of-laparoscopic-nissens-fundoplicationgerdantireflux surgerylaparoscopic nissen’s fundoplication |
| spellingShingle | Cecilia Muvenyi Munguti Bernard Ndung’u A Clinical Audit of Post-Operative Outcomes of Laparoscopic Nissen’s Fundoplication in a Single Center in Sub-Saharan Africa The Annals of African Surgery gerd antireflux surgery laparoscopic nissen’s fundoplication |
| title | A Clinical Audit of Post-Operative Outcomes of Laparoscopic Nissen’s Fundoplication in a Single Center in Sub-Saharan Africa |
| title_full | A Clinical Audit of Post-Operative Outcomes of Laparoscopic Nissen’s Fundoplication in a Single Center in Sub-Saharan Africa |
| title_fullStr | A Clinical Audit of Post-Operative Outcomes of Laparoscopic Nissen’s Fundoplication in a Single Center in Sub-Saharan Africa |
| title_full_unstemmed | A Clinical Audit of Post-Operative Outcomes of Laparoscopic Nissen’s Fundoplication in a Single Center in Sub-Saharan Africa |
| title_short | A Clinical Audit of Post-Operative Outcomes of Laparoscopic Nissen’s Fundoplication in a Single Center in Sub-Saharan Africa |
| title_sort | clinical audit of post operative outcomes of laparoscopic nissen s fundoplication in a single center in sub saharan africa |
| topic | gerd antireflux surgery laparoscopic nissen’s fundoplication |
| url | https://www.annalsofafricansurgery.com/post-operative-outcomes-of-laparoscopic-nissens-fundoplication |
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