Effect of Fc Receptor Genetic Diversity on HIV-1 Disease Pathogenesis

Effect of Fc Receptor Genetic Diversity on HIV-1 Disease Pathogenesis

Fc receptor (FcR) genes collectively have copy number and allelic polymorphisms that have been implicated in multiple inflammatory and autoimmune diseases. This variation might also be involved in etiology of infectious diseases. The protective role of Fc-mediated antibody-function in HIV-1 immunity...

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Bibliographic Details
Main Authors: Daniel E. Geraghty, Christian W. Thorball, Jacques Fellay, Rasmi Thomas
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
next-generation sequencing
polymorphism
disease association
Fc receptors
HIV-1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00970/full

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