High Erk activity suppresses expression of the cell cycle inhibitor p27Kip1 in colorectal cancer cells
<p>Abstract</p> <p>The molecular heterogeneity of human cancer cells at the level of signaling protein activities remains poorly understood. Using a panel of 64 colorectal (CRC) cancer cell lines the activity status of the MAP kinases Erk1 and Erk2 was investigated. Erk1/2 activity...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-02-01
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| Series: | Cell Communication and Signaling |
| Online Access: | http://www.biosignaling.com/content/8/1/1 |