Factors associated with parents’ willingness to enroll their children in trials for COVID-19 vaccination
The coronavirus disease 2019 (COVID-19) pandemic has taken an unprecedented global toll and vaccination is needed to restore healthy living. Timely inclusion of children in vaccination trials is critical. We surveyed caregivers of children seeking care in 17 Emergency Departments (ED) across 6 count...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2021-06-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2020.1834325 |
| _version_ | 1797677210802323456 |
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| author | Ran D. Goldman Georg Staubli Cristina Parra Cotanda Julie C. Brown Julia Hoeffe Michelle Seiler Renana Gelernter Jeanine E. Hall Mark A. Griffiths Adrienne L. Davis Sergio Manzano Ahmed Mater Sara Ahmed David Sheridan Matt Hansen Samina Ali Graham C. Thompson Naoki Shimizu Eileen J. Klein |
| author_facet | Ran D. Goldman Georg Staubli Cristina Parra Cotanda Julie C. Brown Julia Hoeffe Michelle Seiler Renana Gelernter Jeanine E. Hall Mark A. Griffiths Adrienne L. Davis Sergio Manzano Ahmed Mater Sara Ahmed David Sheridan Matt Hansen Samina Ali Graham C. Thompson Naoki Shimizu Eileen J. Klein |
| author_sort | Ran D. Goldman |
| collection | DOAJ |
| description | The coronavirus disease 2019 (COVID-19) pandemic has taken an unprecedented global toll and vaccination is needed to restore healthy living. Timely inclusion of children in vaccination trials is critical. We surveyed caregivers of children seeking care in 17 Emergency Departments (ED) across 6 countries during the peak of the pandemic to identify factors associated with intent to participate in COVID-19 vaccine trials. Questions about child and parent characteristics, COVID-19 expressed concerns and parental attitudes toward participation in a trial were asked. Of 2768 completed surveys, 18.4% parents stated they would enroll their child in a clinical trial for a COVID-19 vaccine and 14.4% would agree to a randomized placebo-controlled study. Factors associated with willingness to participate were parents agreeing to enroll in a COVID-19 vaccine trial themselves (Odds Ratio (OR) 32.9, 95% Confidence Interval (CI) (21.9–51.2)) having an older child (OR 1.0 (1.0–1.01)), having children who received all vaccinations based on their country schedule (OR 2.67 (1.35–5.71)) and parents with high school education or lower (OR 1.79 (1.18–2.74)). Mothers were less likely to enroll their child in a trial (OR 0.68 (0.47–0.97)). Only one fifth of families surveyed will consider enrolling their child in a vaccine trial. Parental interest in participation, history of vaccinating their child, and the child being older all are associated with parents allowing their child to participate in a COVID vaccine trial. This information may help decision-makers and researchers shape their strategies for trial design and participation engagement in upcoming COVID19 vaccination trials. |
| first_indexed | 2024-03-11T22:41:49Z |
| format | Article |
| id | doaj.art-5de10c7e8f784608b4567b8c733ad560 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T22:41:49Z |
| publishDate | 2021-06-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-5de10c7e8f784608b4567b8c733ad5602023-09-22T08:51:52ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2021-06-011761607161110.1080/21645515.2020.18343251834325Factors associated with parents’ willingness to enroll their children in trials for COVID-19 vaccinationRan D. Goldman0Georg Staubli1Cristina Parra Cotanda2Julie C. Brown3Julia Hoeffe4Michelle Seiler5Renana Gelernter6Jeanine E. Hall7Mark A. Griffiths8Adrienne L. Davis9Sergio Manzano10Ahmed Mater11Sara Ahmed12David Sheridan13Matt Hansen14Samina Ali15Graham C. Thompson16Naoki Shimizu17Eileen J. Klein18University of British Columbia, and BC Children’s Hospital Research InstituteUniversity Children’s Hospital ZurichHospital Sant Joan De Déu BarcelonaSeattle Children’s Hospital and University of Washington School of MedicineInselspital University Hospital of BernUniversity Children’s Hospital ZurichTel Aviv UniversityChildren’s Hospital Los Angeles, USC Keck School of MedicineChildren’s Healthcare of Atlanta, Emory School of MedicineHospital for Sick Children and University of TorontoUniversity of GenevaJim Pattison Children’s Hospital, and University of SaskatchewanMary Bridge Children’s HospitalOregon Health & Science University, Doernbecher Children’s HospitalOregon Health & Science University, Doernbecher Children’s HospitalUniversity of AlbertaAlberta Children’s Hospital and University of CalgarySt. Marianna University School of MedicineSeattle Children’s Hospital and University of Washington School of MedicineThe coronavirus disease 2019 (COVID-19) pandemic has taken an unprecedented global toll and vaccination is needed to restore healthy living. Timely inclusion of children in vaccination trials is critical. We surveyed caregivers of children seeking care in 17 Emergency Departments (ED) across 6 countries during the peak of the pandemic to identify factors associated with intent to participate in COVID-19 vaccine trials. Questions about child and parent characteristics, COVID-19 expressed concerns and parental attitudes toward participation in a trial were asked. Of 2768 completed surveys, 18.4% parents stated they would enroll their child in a clinical trial for a COVID-19 vaccine and 14.4% would agree to a randomized placebo-controlled study. Factors associated with willingness to participate were parents agreeing to enroll in a COVID-19 vaccine trial themselves (Odds Ratio (OR) 32.9, 95% Confidence Interval (CI) (21.9–51.2)) having an older child (OR 1.0 (1.0–1.01)), having children who received all vaccinations based on their country schedule (OR 2.67 (1.35–5.71)) and parents with high school education or lower (OR 1.79 (1.18–2.74)). Mothers were less likely to enroll their child in a trial (OR 0.68 (0.47–0.97)). Only one fifth of families surveyed will consider enrolling their child in a vaccine trial. Parental interest in participation, history of vaccinating their child, and the child being older all are associated with parents allowing their child to participate in a COVID vaccine trial. This information may help decision-makers and researchers shape their strategies for trial design and participation engagement in upcoming COVID19 vaccination trials.http://dx.doi.org/10.1080/21645515.2020.1834325coronavirusparental attitudesvaccine trialsdecision-makingglobal survey |
| spellingShingle | Ran D. Goldman Georg Staubli Cristina Parra Cotanda Julie C. Brown Julia Hoeffe Michelle Seiler Renana Gelernter Jeanine E. Hall Mark A. Griffiths Adrienne L. Davis Sergio Manzano Ahmed Mater Sara Ahmed David Sheridan Matt Hansen Samina Ali Graham C. Thompson Naoki Shimizu Eileen J. Klein Factors associated with parents’ willingness to enroll their children in trials for COVID-19 vaccination Human Vaccines & Immunotherapeutics coronavirus parental attitudes vaccine trials decision-making global survey |
| title | Factors associated with parents’ willingness to enroll their children in trials for COVID-19 vaccination |
| title_full | Factors associated with parents’ willingness to enroll their children in trials for COVID-19 vaccination |
| title_fullStr | Factors associated with parents’ willingness to enroll their children in trials for COVID-19 vaccination |
| title_full_unstemmed | Factors associated with parents’ willingness to enroll their children in trials for COVID-19 vaccination |
| title_short | Factors associated with parents’ willingness to enroll their children in trials for COVID-19 vaccination |
| title_sort | factors associated with parents willingness to enroll their children in trials for covid 19 vaccination |
| topic | coronavirus parental attitudes vaccine trials decision-making global survey |
| url | http://dx.doi.org/10.1080/21645515.2020.1834325 |
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