Geriatric sarcopenia is associated with hypertension: A systematic review and meta‐analysis

Abstract This meta‐analysis aimed to explore the potential relationship between senile sarcopenia and hypertension in older people. A comprehensive search was conducted in PubMed, Embase, Web of Science, and the Cochrane Library, up to November 2022. Ten studies comprising 14 804 participants were e...

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Main Authors: Yawen Quan, Chang Wang, Linfeng Wang, Gang Li
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:The Journal of Clinical Hypertension
Subjects:
Online Access:https://doi.org/10.1111/jch.14714
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author Yawen Quan
Chang Wang
Linfeng Wang
Gang Li
author_facet Yawen Quan
Chang Wang
Linfeng Wang
Gang Li
author_sort Yawen Quan
collection DOAJ
description Abstract This meta‐analysis aimed to explore the potential relationship between senile sarcopenia and hypertension in older people. A comprehensive search was conducted in PubMed, Embase, Web of Science, and the Cochrane Library, up to November 2022. Ten studies comprising 14 804 participants were enrolled. The odds ratio (OR) and 95% confidence interval (CI) was pooled to evaluate the correlation between sarcopenia and hypertension in older people utilizing a random‐effects model. Subgroup and sensitivity analyses were then carried out to explore the potential sources of heterogeneity. The results revealed a substantial correlation between sarcopenia and hypertension among older people (OR = 1.39, 95% CI: 1.15–1.67, p < .01). Further subgroup analysis revealed an association between sarcopenic obesity and hypertension (OR = 1.49, 95% CI: 1.37–1.62, p < .01). In conclusions, our findings highlighted a significant relationship between sarcopenia and hypertension among older people, with sarcopenic obesity amplifying this risk.
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spelling doaj.art-5de3457715034319b9d7c973f31a4c972023-10-30T13:26:20ZengWileyThe Journal of Clinical Hypertension1524-61751751-71762023-09-0125980881610.1111/jch.14714Geriatric sarcopenia is associated with hypertension: A systematic review and meta‐analysisYawen Quan0Chang Wang1Linfeng Wang2Gang Li3Department of Geriatric Cardiovascular Diseases Hebei General Hospital Shijiazhuang Hebei ChinaDepartment of Geriatric Cardiovascular Diseases Hebei General Hospital Shijiazhuang Hebei ChinaDepartment of Geriatric Cardiovascular Diseases Hebei General Hospital Shijiazhuang Hebei ChinaDepartment of Geriatric Cardiovascular Diseases Hebei General Hospital Shijiazhuang Hebei ChinaAbstract This meta‐analysis aimed to explore the potential relationship between senile sarcopenia and hypertension in older people. A comprehensive search was conducted in PubMed, Embase, Web of Science, and the Cochrane Library, up to November 2022. Ten studies comprising 14 804 participants were enrolled. The odds ratio (OR) and 95% confidence interval (CI) was pooled to evaluate the correlation between sarcopenia and hypertension in older people utilizing a random‐effects model. Subgroup and sensitivity analyses were then carried out to explore the potential sources of heterogeneity. The results revealed a substantial correlation between sarcopenia and hypertension among older people (OR = 1.39, 95% CI: 1.15–1.67, p < .01). Further subgroup analysis revealed an association between sarcopenic obesity and hypertension (OR = 1.49, 95% CI: 1.37–1.62, p < .01). In conclusions, our findings highlighted a significant relationship between sarcopenia and hypertension among older people, with sarcopenic obesity amplifying this risk.https://doi.org/10.1111/jch.14714hypertensionmeta‐analysisolder adultsarcopenia
spellingShingle Yawen Quan
Chang Wang
Linfeng Wang
Gang Li
Geriatric sarcopenia is associated with hypertension: A systematic review and meta‐analysis
The Journal of Clinical Hypertension
hypertension
meta‐analysis
older adult
sarcopenia
title Geriatric sarcopenia is associated with hypertension: A systematic review and meta‐analysis
title_full Geriatric sarcopenia is associated with hypertension: A systematic review and meta‐analysis
title_fullStr Geriatric sarcopenia is associated with hypertension: A systematic review and meta‐analysis
title_full_unstemmed Geriatric sarcopenia is associated with hypertension: A systematic review and meta‐analysis
title_short Geriatric sarcopenia is associated with hypertension: A systematic review and meta‐analysis
title_sort geriatric sarcopenia is associated with hypertension a systematic review and meta analysis
topic hypertension
meta‐analysis
older adult
sarcopenia
url https://doi.org/10.1111/jch.14714
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AT changwang geriatricsarcopeniaisassociatedwithhypertensionasystematicreviewandmetaanalysis
AT linfengwang geriatricsarcopeniaisassociatedwithhypertensionasystematicreviewandmetaanalysis
AT gangli geriatricsarcopeniaisassociatedwithhypertensionasystematicreviewandmetaanalysis