A specific E3 ligase/deubiquitinase pair modulates TBP protein levels during muscle differentiation

A specific E3 ligase/deubiquitinase pair modulates TBP protein levels during muscle differentiation

TFIID—a complex of TATA-binding protein (TBP) and TBP-associated factors (TAFs)—is a central component of the Pol II promoter recognition apparatus. Recent studies have revealed significant downregulation of TFIID subunits in terminally differentiated myocytes, hepatocytes and adipocytes. Here, we r...

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Bibliographic Details
Main Authors: Li Li, Silvia Sanchez Martinez, Wenxin Hu, Zhe Liu, Robert Tjian
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-09-01
Series:eLife
Subjects:
TBP
ubiquitination
Huwe1
USP10
differentitation
Online Access:https://elifesciences.org/articles/08536

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