Pharmacokinetics, Tissue Distribution, Plasma Protein Binding Studies of 10-Dehydroxyl-12-Demethoxy-Conophylline, a Novel Anti-Tumor Candidate, in Rats

Pharmacokinetics, Tissue Distribution, Plasma Protein Binding Studies of 10-Dehydroxyl-12-Demethoxy-Conophylline, a Novel Anti-Tumor Candidate, in Rats

10-Dehydroxyl-12-demethoxy-conophylline is a natural anticancer candidate. The motivation of this study was to explore the pharmacokinetic profiles, tissue distribution, and plasma protein binding of 10-dehydroxyl-12-demethoxy-conophylline in Sprague Dawley rats. A rapid, sensitive, and specific ult...

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Bibliographic Details
Main Authors:	Chengjun Jiang, Jie Li, Xianghai Cai, Nini Li, Yan Guo, Dianlei Wang
Format:	Article
Language:	English
Published:	MDPI AG 2019-01-01
Series:	Molecules
Subjects:	10-dehydroxyl-12-demethoxy-conophylline pharmacokinetics tissue distribution protein binding rate
Online Access:	http://www.mdpi.com/1420-3049/24/2/283

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