EFFECTS OF RENAL ARTERY DENERVATION ON LEFT VENTRICULAR DEFORMATION AND BLOOD FLOW VELOCITY IN THE DISTAL SEGMENT OF ANTERIOR DESCENDING CORONARY ARTERY AMONG PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION
Aim. To assess the dynamics of left ventricular (LV) longitudinal deformation and blood flow velocity in the distal segment of anterior descending coronary artery (ADCA) among patients with resistant arterial hypertension (AH) 12 months after renal artery denervation.Material and methods. In seven p...
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«FIRMA «SILICEA» LLC
2014-04-01
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Online Access: | https://russjcardiol.elpub.ru/jour/article/view/44 |
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author | E. N. Pavlukova V. F. Mordovin V. V. Pekarskyi V. A. Lichikaki R. S. Karpov |
author_facet | E. N. Pavlukova V. F. Mordovin V. V. Pekarskyi V. A. Lichikaki R. S. Karpov |
author_sort | E. N. Pavlukova |
collection | DOAJ |
description | Aim. To assess the dynamics of left ventricular (LV) longitudinal deformation and blood flow velocity in the distal segment of anterior descending coronary artery (ADCA) among patients with resistant arterial hypertension (AH) 12 months after renal artery denervation.Material and methods. In seven patients with resistant AH (mean age 52,00±6,59 years), bilateral renal artery denervation was performed. Five out of seven patients had concentric LV hypertrophy. The complex clinical and instrumental examination included the assessment of office and 24-hour blood pressure (BP) levels, echocardiography, speckle tracking imaging (2D strain), and transthoracic visualisation of the distal segment of ADCA.Results. Twelve months after renal artery denervation, office BP levels decreased by 31/20 mm Hg. Mean 24-hour, mean daytime, and mean nighttime BP levels reduced by 15,58/14,62 mm Hg, 17,1/14,9 mm Hg, and by 21,1/14,47 mm Hg, respectively. There was an increase in global longitudinal LV deformation and local LV deformation (basal septal segment, basal and middle segments ofanterior and posterior walls, and middle and apical segments of lateral wall). The improvement in longitudinal systolic LV function was associated with reduced linear velocity of diastolic blood flow in the distal ADCA segment, without similar systolic changes.Conclusion. Our results suggest that renal artery denervation is linked to improved LV function; therefore, this method could be widely recommended for the management of patients with resistant AH. |
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spelling | doaj.art-5ded014c3cdd4ade96ee074b7fdfb0562023-03-29T21:23:21Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202014-04-010410010710.15829/1560-4071-2014-4-100-10744EFFECTS OF RENAL ARTERY DENERVATION ON LEFT VENTRICULAR DEFORMATION AND BLOOD FLOW VELOCITY IN THE DISTAL SEGMENT OF ANTERIOR DESCENDING CORONARY ARTERY AMONG PATIENTS WITH RESISTANT ARTERIAL HYPERTENSIONE. N. Pavlukova0V. F. Mordovin1V. V. Pekarskyi2V. A. Lichikaki3R. S. Karpov4Research Institute of Cardiology, Siberian Branch, Russian Academy of Medical Sciences, Tomsk, RussiaResearch Institute of Cardiology, Siberian Branch, Russian Academy of Medical Sciences, Tomsk, RussiaResearch Institute of Cardiology, Siberian Branch, Russian Academy of Medical Sciences, Tomsk, RussiaResearch Institute of Cardiology, Siberian Branch, Russian Academy of Medical Sciences, Tomsk, RussiaResearch Institute of Cardiology, Siberian Branch, Russian Academy of Medical Sciences, Tomsk, RussiaAim. To assess the dynamics of left ventricular (LV) longitudinal deformation and blood flow velocity in the distal segment of anterior descending coronary artery (ADCA) among patients with resistant arterial hypertension (AH) 12 months after renal artery denervation.Material and methods. In seven patients with resistant AH (mean age 52,00±6,59 years), bilateral renal artery denervation was performed. Five out of seven patients had concentric LV hypertrophy. The complex clinical and instrumental examination included the assessment of office and 24-hour blood pressure (BP) levels, echocardiography, speckle tracking imaging (2D strain), and transthoracic visualisation of the distal segment of ADCA.Results. Twelve months after renal artery denervation, office BP levels decreased by 31/20 mm Hg. Mean 24-hour, mean daytime, and mean nighttime BP levels reduced by 15,58/14,62 mm Hg, 17,1/14,9 mm Hg, and by 21,1/14,47 mm Hg, respectively. There was an increase in global longitudinal LV deformation and local LV deformation (basal septal segment, basal and middle segments ofanterior and posterior walls, and middle and apical segments of lateral wall). The improvement in longitudinal systolic LV function was associated with reduced linear velocity of diastolic blood flow in the distal ADCA segment, without similar systolic changes.Conclusion. Our results suggest that renal artery denervation is linked to improved LV function; therefore, this method could be widely recommended for the management of patients with resistant AH.https://russjcardiol.elpub.ru/jour/article/view/44resistant arterial hypertensionrenal artery denervationleft ventricular deformationspeckle tracking imaging (2d strain)coronary blood flow |
spellingShingle | E. N. Pavlukova V. F. Mordovin V. V. Pekarskyi V. A. Lichikaki R. S. Karpov EFFECTS OF RENAL ARTERY DENERVATION ON LEFT VENTRICULAR DEFORMATION AND BLOOD FLOW VELOCITY IN THE DISTAL SEGMENT OF ANTERIOR DESCENDING CORONARY ARTERY AMONG PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION Российский кардиологический журнал resistant arterial hypertension renal artery denervation left ventricular deformation speckle tracking imaging (2d strain) coronary blood flow |
title | EFFECTS OF RENAL ARTERY DENERVATION ON LEFT VENTRICULAR DEFORMATION AND BLOOD FLOW VELOCITY IN THE DISTAL SEGMENT OF ANTERIOR DESCENDING CORONARY ARTERY AMONG PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION |
title_full | EFFECTS OF RENAL ARTERY DENERVATION ON LEFT VENTRICULAR DEFORMATION AND BLOOD FLOW VELOCITY IN THE DISTAL SEGMENT OF ANTERIOR DESCENDING CORONARY ARTERY AMONG PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION |
title_fullStr | EFFECTS OF RENAL ARTERY DENERVATION ON LEFT VENTRICULAR DEFORMATION AND BLOOD FLOW VELOCITY IN THE DISTAL SEGMENT OF ANTERIOR DESCENDING CORONARY ARTERY AMONG PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION |
title_full_unstemmed | EFFECTS OF RENAL ARTERY DENERVATION ON LEFT VENTRICULAR DEFORMATION AND BLOOD FLOW VELOCITY IN THE DISTAL SEGMENT OF ANTERIOR DESCENDING CORONARY ARTERY AMONG PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION |
title_short | EFFECTS OF RENAL ARTERY DENERVATION ON LEFT VENTRICULAR DEFORMATION AND BLOOD FLOW VELOCITY IN THE DISTAL SEGMENT OF ANTERIOR DESCENDING CORONARY ARTERY AMONG PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION |
title_sort | effects of renal artery denervation on left ventricular deformation and blood flow velocity in the distal segment of anterior descending coronary artery among patients with resistant arterial hypertension |
topic | resistant arterial hypertension renal artery denervation left ventricular deformation speckle tracking imaging (2d strain) coronary blood flow |
url | https://russjcardiol.elpub.ru/jour/article/view/44 |
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