Level of Foxp3, DNMTs, methylation of Foxp3 promoter region, and CD4 + CD25 + CD127low regulatory T cells in vulvar lichen sclerosus

Level of Foxp3, DNMTs, methylation of Foxp3 promoter region, and CD4 + CD25 + CD127low regulatory T cells in vulvar lichen sclerosus

Abstract This study is to investigate the pathogenesis of vulvar lichen sclerosus (VLS) by analyzing the level of Foxp3, DNMTs, methylation of Foxp3 promoter region, and CD4 + CD25 + CD127low Regulatory T cells (Tregs). This study enrolled 15 VLS patients and 25 controls. Lesional and extralesional...

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Bibliographic Details
Main Authors: Lin Wang, Jin‐Ling Yi, Hai‐Yan Chen, Pei‐Liang Wang, Yan‐Li Shen
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
CD127
CD4 + CD25+ Treg
Foxp3
methylation
vulvar lichen sclerosus
Online Access:https://doi.org/10.1002/kjm2.12356

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