Recent Advances in the Molecular Design and Applications of Multispecific Biotherapeutics
Recombinant protein-based biotherapeutics drugs have transformed clinical pipelines of the biopharmaceutical industry since the launch of recombinant insulin nearly four decades ago. These biologic drugs are structurally more complex than small molecules, and yet share a similar principle for ration...
Main Authors: | Xiaotian Zhong, Aaron M. D’Antona |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-03-01
|
Series: | Antibodies |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4468/10/2/13 |
Similar Items
-
Design of antibody variable fragments with reduced reactivity to preexisting anti-drug antibodies
by: Maria U. Johansson, et al.
Published: (2023-12-01) -
Principles and Current Clinical Landscape of Multispecific Antibodies against Cancer
by: Mariam Elshiaty, et al.
Published: (2021-05-01) -
Identification of Mispairing Omic Signatures in Chinese Hamster Ovary (CHO) Cells Producing a Tri-Specific Antibody
by: Maria João Sebastião, et al.
Published: (2023-10-01) -
Engineered mRNA and the Rise of Next-Generation Antibodies
by: Laura Sanz, et al.
Published: (2021-09-01) -
Selection of bispecific antibodies with optimal developability using FcRn‑pH‑HPLC as an optimized FcRn affinity chromatography method
by: Thomas Müller, et al.
Published: (2023-12-01)