Research progress on black phosphorus hybrids hydrogel platforms for biomedical applications

Abstract Hydrogels, also known as three-dimensional, flexible, and polymer networks, are composed of natural and/or synthetic polymers with exceptional properties such as hydrophilicity, biocompatibility, biofunctionality, and elasticity. Researchers in biomedicine, biosensing, pharmaceuticals, ener...

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Main Authors: Hao-xuan Li, Kun-chi Zhao, Jia-jia Jiang, Qing-san Zhu
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Biological Engineering
Subjects:
Online Access:https://doi.org/10.1186/s13036-023-00328-w
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author Hao-xuan Li
Kun-chi Zhao
Jia-jia Jiang
Qing-san Zhu
author_facet Hao-xuan Li
Kun-chi Zhao
Jia-jia Jiang
Qing-san Zhu
author_sort Hao-xuan Li
collection DOAJ
description Abstract Hydrogels, also known as three-dimensional, flexible, and polymer networks, are composed of natural and/or synthetic polymers with exceptional properties such as hydrophilicity, biocompatibility, biofunctionality, and elasticity. Researchers in biomedicine, biosensing, pharmaceuticals, energy and environment, agriculture, and cosmetics are interested in hydrogels. Hydrogels have limited adaptability for complicated biological information transfer in biomedical applications due to their lack of electrical conductivity and low mechanical strength, despite significant advances in the development and use of hydrogels. The nano-filler-hydrogel hybrid system based on supramolecular interaction between host and guest has emerged as one of the potential solutions to the aforementioned issues. Black phosphorus, as one of the representatives of novel two-dimensional materials, has gained a great deal of interest in recent years owing to its exceptional physical and chemical properties, among other nanoscale fillers. However, a few numbers of publications have elaborated on the scientific development of black phosphorus hybrid hydrogels extensively. In this review, this review thus summarized the benefits of black phosphorus hybrid hydrogels and highlighted the most recent biological uses of black phosphorus hybrid hydrogels. Finally, the difficulties and future possibilities of the development of black phosphorus hybrid hydrogels are reviewed in an effort to serve as a guide for the application and manufacture of black phosphorus -based hydrogels. Graphical Abstract Recent applications of black phosphorus hybrid hydrogels in biomedicine.
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spelling doaj.art-5df51db4888d4acf899d91dc048e80b12023-02-05T12:15:16ZengBMCJournal of Biological Engineering1754-16112023-01-0117111810.1186/s13036-023-00328-wResearch progress on black phosphorus hybrids hydrogel platforms for biomedical applicationsHao-xuan Li0Kun-chi Zhao1Jia-jia Jiang2Qing-san Zhu3Department of Spine Surgery, China-Japan Union Hospital of Jilin UniversityDepartment of Spine Surgery, China-Japan Union Hospital of Jilin UniversityDepartment of Spine Surgery, China-Japan Union Hospital of Jilin UniversityDepartment of Spine Surgery, China-Japan Union Hospital of Jilin UniversityAbstract Hydrogels, also known as three-dimensional, flexible, and polymer networks, are composed of natural and/or synthetic polymers with exceptional properties such as hydrophilicity, biocompatibility, biofunctionality, and elasticity. Researchers in biomedicine, biosensing, pharmaceuticals, energy and environment, agriculture, and cosmetics are interested in hydrogels. Hydrogels have limited adaptability for complicated biological information transfer in biomedical applications due to their lack of electrical conductivity and low mechanical strength, despite significant advances in the development and use of hydrogels. The nano-filler-hydrogel hybrid system based on supramolecular interaction between host and guest has emerged as one of the potential solutions to the aforementioned issues. Black phosphorus, as one of the representatives of novel two-dimensional materials, has gained a great deal of interest in recent years owing to its exceptional physical and chemical properties, among other nanoscale fillers. However, a few numbers of publications have elaborated on the scientific development of black phosphorus hybrid hydrogels extensively. In this review, this review thus summarized the benefits of black phosphorus hybrid hydrogels and highlighted the most recent biological uses of black phosphorus hybrid hydrogels. Finally, the difficulties and future possibilities of the development of black phosphorus hybrid hydrogels are reviewed in an effort to serve as a guide for the application and manufacture of black phosphorus -based hydrogels. Graphical Abstract Recent applications of black phosphorus hybrid hydrogels in biomedicine.https://doi.org/10.1186/s13036-023-00328-wBlack phosphorus (BP)Hybrid hydrogelsNanomaterialsBiomedical applicationsTissue engineering
spellingShingle Hao-xuan Li
Kun-chi Zhao
Jia-jia Jiang
Qing-san Zhu
Research progress on black phosphorus hybrids hydrogel platforms for biomedical applications
Journal of Biological Engineering
Black phosphorus (BP)
Hybrid hydrogels
Nanomaterials
Biomedical applications
Tissue engineering
title Research progress on black phosphorus hybrids hydrogel platforms for biomedical applications
title_full Research progress on black phosphorus hybrids hydrogel platforms for biomedical applications
title_fullStr Research progress on black phosphorus hybrids hydrogel platforms for biomedical applications
title_full_unstemmed Research progress on black phosphorus hybrids hydrogel platforms for biomedical applications
title_short Research progress on black phosphorus hybrids hydrogel platforms for biomedical applications
title_sort research progress on black phosphorus hybrids hydrogel platforms for biomedical applications
topic Black phosphorus (BP)
Hybrid hydrogels
Nanomaterials
Biomedical applications
Tissue engineering
url https://doi.org/10.1186/s13036-023-00328-w
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AT jiajiajiang researchprogressonblackphosphorushybridshydrogelplatformsforbiomedicalapplications
AT qingsanzhu researchprogressonblackphosphorushybridshydrogelplatformsforbiomedicalapplications