CD93 Correlates With Immune Infiltration and Impacts Patient Immunotherapy Efficacy: A Pan-Cancer Analysis

CD93 Correlates With Immune Infiltration and Impacts Patient Immunotherapy Efficacy: A Pan-Cancer Analysis

Background: The clinical implementation of immune-checkpoint inhibitors (ICIs) targeting CTLA4, PD-1, and PD-L1 has revolutionized the treatment of cancer. However, the majority of patients do not derive clinical benefit. Further development is needed to optimize the approach of ICI therapy. Immunot...

Full description

Bibliographic Details
Main Authors:	Zerui Zhang, Mengli Zheng, Qiang Ding, Mei Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-02-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	CD93 pan-cancer tumor immunity TME immunotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2022.817965/full

Similar Items

Identify the immune characteristics and immunotherapy value of CD93 in the pan-cancer based on the public data sets
by: Aiyuan Guo, et al.
Published: (2022-10-01)

Pan-cancer analysis of ADAMs: A promising biomarker for prognosis and response to chemotherapy and immunotherapy
by: Bo Ma, et al.
Published: (2023-04-01)

CD93 overexpresses in liver hepatocellular carcinoma and represents a potential immunotherapy target
by: Qianwei Jiang, et al.
Published: (2023-07-01)

Role of CD93 in Health and Disease
by: Giovanni Tossetta, et al.
Published: (2023-07-01)

Pan-Cancer Analysis of the TRP Family, Especially TRPV4 and TRPC4, and Its Expression Correlated with Prognosis, Tumor Microenvironment, and Treatment Sensitivity
by: Zhenghao Chen, et al.
Published: (2023-02-01)

Multi-omics profiling and digital image analysis reveal the potential prognostic and immunotherapeutic properties of CD93 in stomach adenocarcinoma
by: Baokang Wu, et al.
Published: (2023-01-01)

Characterization of the immune cell infiltration landscape in myxofibrosarcoma to aid immunotherapy
by: Zi-Yue Zhao, et al.
Published: (2022-07-01)

Pan-Cancer Analysis of OLFML2B Expression and Its Association With Prognosis and Immune Infiltration
by: Pengbo Hu, et al.
Published: (2022-07-01)

Bioinformatics Approaches to Predict Mutation Effects in the Binding Site of the Proangiogenic Molecule CD93
by: Vittoria Cicaloni, et al.
Published: (2022-06-01)

A Systematic Immune and Prognostic Analysis of CD48 Interaction with Tumor Microenvironment in Pan-Cancer
by: He M, et al.
Published: (2023-11-01)

Pan-cancer and single-cell analyses identify CD44 as an immunotherapy response predictor and regulating macrophage polarization and tumor progression in colorectal cancer
by: Qian Zhang, et al.
Published: (2024-03-01)

A Pan-Cancer Analysis of Prognostic and Immunological Roles for Cell Death Genes
by: Ye Hong, et al.
Published: (2023-05-01)

The Role of m6A Regulator-Mediated Methylation Modification and Tumor Microenvironment Infiltration in Glioblastoma Multiforme
by: Liang Wang, et al.
Published: (2022-02-01)

Cancer-testis antigen CEP55 serves as a prognostic biomarker and is correlated with immune infiltration and immunotherapy efficacy in pan-cancer
by: Xiaodong Xie, et al.
Published: (2023-07-01)

Pan-cancer analyses of clinical prognosis, immune infiltration, and immunotherapy efficacy for TRPV family using multi-omics data
by: Chong Shen, et al.
Published: (2023-06-01)

Evaluation of CD93hi macrophage on atherosclerosis through dynamic cells adoptive transfer
by: Chen Su, et al.
Published: (2023-07-01)

Large-Scale Single-Cell and Bulk Sequencing Analyses Reveal the Prognostic Value and Immune Aspects of CD147 in Pan-Cancer
by: Jingwei Zhang, et al.
Published: (2022-04-01)

CXCL11 Correlates with Immune Infiltration and Impacts Patient Immunotherapy Efficacy: A Pan-Cancer Analysis
by: Yang Li, et al.
Published: (2022-07-01)

Psoriasis and Pro-angiogenetic Factor CD93: Gene Expression and Association with Gene Polymorphism Suggests a Role in Disease Pathogenesis
by: Albert Duvetorp, et al.
Published: (2017-06-01)

GIMAP7 as a Potential Predictive Marker for Pan-Cancer Prognosis and Immunotherapy Efficacy
by: Qin Y, et al.
Published: (2022-02-01)

Distinct roles of CD244 expression in cancer diagnosis and prognosis: A pan-cancer analysis
by: Zhenzhen Deng, et al.
Published: (2024-04-01)

Level studies of 93Mo via 93Nb(p, nγ)93Mo reaction and density of discrete levels in 93Mo
by: Razavi Rohallah, et al.
Published: (2011-01-01)

Roles of HMGBs in Prognosis and Immunotherapy: A Pan-Cancer Analysis
by: Tong Lin, et al.
Published: (2021-10-01)

Impact of NSCLC metabolic remodeling on immunotherapy effectiveness
by: Lulu Lv, et al.
Published: (2022-08-01)

Pan-cancer analysis identifies the correlations of Thymosin Beta 10 with predicting prognosis and immunotherapy response
by: Zhanzhan Li, et al.
Published: (2023-05-01)

ORC6, a novel prognostic biomarker, correlates with T regulatory cell infiltration in prostate adenocarcinoma: a pan-cancer analysis
by: Yuan Lin, et al.
Published: (2023-03-01)

Comprehensive Analysis Reveals Distinct Immunological and Prognostic Characteristics of CD276/B7-H3 in Pan-Cancer
by: Ding J, et al.
Published: (2023-02-01)

Comprehensive Landscape of RRM2 with Immune Infiltration in Pan-Cancer
by: Zijian Zhou, et al.
Published: (2022-06-01)

A pan-cancer and single-cell sequencing analysis of CD161, a promising onco-immunological biomarker in tumor microenvironment and immunotherapy
by: He Li, et al.
Published: (2022-12-01)

Comprehensive Pan-Cancer Analysis of Senescence With Cancer Prognosis and Immunotherapy
by: Qinfei Zhao, et al.
Published: (2022-07-01)

Interaction, immune infiltration characteristics and prognostic modeling of efferocytosis-related subtypes in glioblastoma
by: Songyun Zhao, et al.
Published: (2023-10-01)

Angiogenesis modulated by CD93 and its natural ligands IGFBP7 and MMRN2: a new target to facilitate solid tumor therapy by vasculature normalization
by: Yang Li, et al.
Published: (2023-09-01)

Development of a c-MET x CD137 bispecific antibody for targeted immune agonism in cancer immunotherapy
by: Hong Zhang, et al.
Published: (2024-01-01)

The epiphany derived from T-cell–inflamed profiles: Pan-cancer characterization of CD8A as a biomarker spanning clinical relevance, cancer prognosis, immunosuppressive environment, and treatment responses
by: Decao Niu, et al.
Published: (2022-08-01)

Evidence of Omics, Immune Infiltration, and Pharmacogenomics for BATF in a Pan-Cancer Cohort
by: Chenguang Jia, et al.
Published: (2022-04-01)

Immunologic Gene Sets Reveal Features of the Tumor Immune Microenvironment and Predict Prognosis and Immunotherapy Response: A Pan-Cancer Analysis
by: Hongda Pan, et al.
Published: (2022-04-01)

Research progress of extracellular vesicles as biomarkers in immunotherapy for non-small cell lung cancer
by: Yang Ge, et al.
Published: (2023-04-01)

Pan-Cancer Analysis of the Oncogenic and Immunological Role of RCN3: A Potential Biomarker for Prognosis and Immunotherapy
by: Jian Ding, et al.
Published: (2022-05-01)

The role of Angiogenesis and remodeling (AR) associated signature for predicting prognosis and clinical outcome of immunotherapy in pan-cancer
by: Xiaojiao Sun, et al.
Published: (2022-11-01)

Prediction of prognosis, immune infiltration, and personalized treatment of hepatocellular carcinoma by analysis of cuproptosis-related long noncoding RNAs and verification in vitro
by: Shanbao Li, et al.
Published: (2023-09-01)