Impact of Histone Lysine Methyltransferase SUV4-20H2 on Cancer Onset and Progression with Therapeutic Potential

Impact of Histone Lysine Methyltransferase SUV4-20H2 on Cancer Onset and Progression with Therapeutic Potential

Histone lysine methyltransferase SUV4-20H2, a member of the suppressor of variegation 4–20 homolog (SUV4-20) family, has a critical impact on the regulation of chromatin structure and gene expression. This methyltransferase establishes the trimethylation of histone H4 lysine 20 (H4K20me3), a repress...

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Bibliographic Details
Main Authors: Stela Papadaki, Christina Piperi
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
lysine methyltransferase
epigenome
epigenetic modifications
chromatin compaction
heterochromatin
gene regulation
Online Access:https://www.mdpi.com/1422-0067/25/5/2498

Internet

https://www.mdpi.com/1422-0067/25/5/2498

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