Optimization Models for Reaction Networks: Information Divergence, Quadratic Programming and Kirchhoff’s Laws

This article presents a simple derivation of optimization models for reaction networks leading to a generalized form of the mass-action law, and compares the formal structure of Minimum Information Divergence, Quadratic Programming and Kirchhoff type network models. These optimization models are use...

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Bibliographic Details
Main Authors: Julio Michael Stern, Fabio Nakano
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Axioms
Subjects:
Online Access:http://www.mdpi.com/2075-1680/3/1/109
Description
Summary:This article presents a simple derivation of optimization models for reaction networks leading to a generalized form of the mass-action law, and compares the formal structure of Minimum Information Divergence, Quadratic Programming and Kirchhoff type network models. These optimization models are used in related articles to develop and illustrate the operation of ontology alignment algorithms and to discuss closely connected issues concerning the epistemological and statistical significance of sharp or precise hypotheses in empirical science.
ISSN:2075-1680