Joint control of meiotic crossover patterning by the synaptonemal complex and HEI10 dosage
During meiosis, the number and distribution of crossovers (COs) are tightly controlled, but the mechanistic basis of this control is unclear. Here, by combining experimental data and mathematical modeling, the study advocates a CO patterning model via coarsening through the diffusion of HEI10 along...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-33472-w |
| _version_ | 1817983900856614912 |
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| author | Stéphanie Durand Qichao Lian Juli Jing Marcel Ernst Mathilde Grelon David Zwicker Raphael Mercier |
| author_facet | Stéphanie Durand Qichao Lian Juli Jing Marcel Ernst Mathilde Grelon David Zwicker Raphael Mercier |
| author_sort | Stéphanie Durand |
| collection | DOAJ |
| description | During meiosis, the number and distribution of crossovers (COs) are tightly controlled, but the mechanistic basis of this control is unclear. Here, by combining experimental data and mathematical modeling, the study advocates a CO patterning model via coarsening through the diffusion of HEI10 along the synaptonemal complex. |
| first_indexed | 2024-04-13T23:38:56Z |
| format | Article |
| id | doaj.art-5e0b7a6803c842ca8ff4d9fc6fa8bc96 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-13T23:38:56Z |
| publishDate | 2022-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-5e0b7a6803c842ca8ff4d9fc6fa8bc962022-12-22T02:24:36ZengNature PortfolioNature Communications2041-17232022-10-0113111310.1038/s41467-022-33472-wJoint control of meiotic crossover patterning by the synaptonemal complex and HEI10 dosageStéphanie Durand0Qichao Lian1Juli Jing2Marcel Ernst3Mathilde Grelon4David Zwicker5Raphael Mercier6Department of Chromosome Biology, Max Planck Institute for Plant Breeding ResearchDepartment of Chromosome Biology, Max Planck Institute for Plant Breeding ResearchDepartment of Chromosome Biology, Max Planck Institute for Plant Breeding ResearchMax Planck Institute for Dynamics and Self-OrganizationUniversité Paris-Saclay, INRAE, AgroParisTech, Institut Jean-Pierre Bourgin (IJPB)Max Planck Institute for Dynamics and Self-OrganizationDepartment of Chromosome Biology, Max Planck Institute for Plant Breeding ResearchDuring meiosis, the number and distribution of crossovers (COs) are tightly controlled, but the mechanistic basis of this control is unclear. Here, by combining experimental data and mathematical modeling, the study advocates a CO patterning model via coarsening through the diffusion of HEI10 along the synaptonemal complex.https://doi.org/10.1038/s41467-022-33472-w |
| spellingShingle | Stéphanie Durand Qichao Lian Juli Jing Marcel Ernst Mathilde Grelon David Zwicker Raphael Mercier Joint control of meiotic crossover patterning by the synaptonemal complex and HEI10 dosage Nature Communications |
| title | Joint control of meiotic crossover patterning by the synaptonemal complex and HEI10 dosage |
| title_full | Joint control of meiotic crossover patterning by the synaptonemal complex and HEI10 dosage |
| title_fullStr | Joint control of meiotic crossover patterning by the synaptonemal complex and HEI10 dosage |
| title_full_unstemmed | Joint control of meiotic crossover patterning by the synaptonemal complex and HEI10 dosage |
| title_short | Joint control of meiotic crossover patterning by the synaptonemal complex and HEI10 dosage |
| title_sort | joint control of meiotic crossover patterning by the synaptonemal complex and hei10 dosage |
| url | https://doi.org/10.1038/s41467-022-33472-w |
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