PTEN in Colorectal Cancer: Shedding Light on Its Role as Predictor and Target

PTEN in Colorectal Cancer: Shedding Light on Its Role as Predictor and Target

Molecular assessment of colorectal cancer (CRC) is receiving growing attention, beyond RAS and BRAF, because of its influence on prognosis and prediction in cancer treatment. PTEN (phosphatase and tensin homologue), a tumor suppressor, regulating cell division and apoptosis, has been explored, and s...

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Bibliographic Details
Main Authors: Lisa Salvatore, Maria Alessandra Calegari, Fotios Loupakis, Matteo Fassan, Brunella Di Stefano, Maria Bensi, Emilio Bria, Giampaolo Tortora
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cancers
Subjects:
pten
colorectal cancer
target therapy
bevacizumab
anti-egfr
Online Access:https://www.mdpi.com/2072-6694/11/11/1765

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