Case-controlled study of tuberculosis in in-vitro fertilisation-embryo transfer and natural pregnancy
Abstract Objective To improve the understanding of the clinical features and imaging characteristics of pregnant women with and without in-vitro fertilisation-embryo transfer combined with pulmonary tuberculosis (TB). Methods A retrospective analysis was conducted involving 50 patients with pregnanc...
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | BMC Pregnancy and Childbirth |
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| Online Access: | https://doi.org/10.1186/s12884-024-06260-1 |
| _version_ | 1797276259483385856 |
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| author | Jia-Lu Wei Le Zhang Yan-Ling Xu Wei Gan Min Qi Xu-Wen Fu Xiang Li |
| author_facet | Jia-Lu Wei Le Zhang Yan-Ling Xu Wei Gan Min Qi Xu-Wen Fu Xiang Li |
| author_sort | Jia-Lu Wei |
| collection | DOAJ |
| description | Abstract Objective To improve the understanding of the clinical features and imaging characteristics of pregnant women with and without in-vitro fertilisation-embryo transfer combined with pulmonary tuberculosis (TB). Methods A retrospective analysis was conducted involving 50 patients with pregnancy who had pulmonary TB and were admitted to the Third People’s Hospital of Kunming (China) between 1 January 2017 and 31 December 2021. These patients were divided into an in-vitro fertilisation and embryo transfer (IVF-ET) conception group and a natural conception group according to the conception method. The clinical and imaging data were then collected and compared. Results The mean age of the IVF-ET group (n = 13, 31.85 ± 5.84 years) was higher than in the natural conception group (n = 37, 27.05 ± 5.5 years). The proportions of fever, haematogenous TB and extrapulmonary TB in the IVF-ET group (92.31%, 84.62% and 76.92%, respectively) were higher than those in the natural conception group (40.54%,16.22%,27.03%,respectively). The percentage of patients with pregnancy who had intracranial TB (76.9%) in the IVF-ET group was higher than in the natural conception group (10.8%). The percentage of pregnancy terminations in the IVF-ET conception group (84.62%) was higher than in the natural conception group (48.65%). All the above results had statistically significant differences (p < 0.05). Conclusion Overall, IVF-ET conception combined with extensive pulmonary TB lesions lead to heavy systemic toxic symptoms, severe disease and poor pregnancy outcomes. Therefore, screening for TB prior to performing IVF-ET is recommended. |
| first_indexed | 2024-03-07T15:24:45Z |
| format | Article |
| id | doaj.art-5e13c1d5c652431d971b51484f80eb20 |
| institution | Directory Open Access Journal |
| issn | 1471-2393 |
| language | English |
| last_indexed | 2024-03-07T15:24:45Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pregnancy and Childbirth |
| spelling | doaj.art-5e13c1d5c652431d971b51484f80eb202024-03-05T17:08:38ZengBMCBMC Pregnancy and Childbirth1471-23932024-01-012411810.1186/s12884-024-06260-1Case-controlled study of tuberculosis in in-vitro fertilisation-embryo transfer and natural pregnancyJia-Lu Wei0Le Zhang1Yan-Ling Xu2Wei Gan3Min Qi4Xu-Wen Fu5Xiang Li6Department of Radiology, The Third People’s Hospital of Kunming/Yunnan Clinical Medical Center for Infectious DiseasesDepartment of ICU, The Third People’s Hospital of Kunming/Yunnan Clinical Medical Center for Infectious DiseasesDepartment of Radiology, The Third People’s Hospital of Kunming/Yunnan Clinical Medical Center for Infectious DiseasesDepartment of Radiology, The Third People’s Hospital of Kunming/Yunnan Clinical Medical Center for Infectious DiseasesDepartment of Radiology, The Third People’s Hospital of Kunming/Yunnan Clinical Medical Center for Infectious DiseasesDepartment of Radiology, The Third People’s Hospital of Kunming/Yunnan Clinical Medical Center for Infectious DiseasesDepartment of Radiology, The Third People’s Hospital of Kunming/Yunnan Clinical Medical Center for Infectious DiseasesAbstract Objective To improve the understanding of the clinical features and imaging characteristics of pregnant women with and without in-vitro fertilisation-embryo transfer combined with pulmonary tuberculosis (TB). Methods A retrospective analysis was conducted involving 50 patients with pregnancy who had pulmonary TB and were admitted to the Third People’s Hospital of Kunming (China) between 1 January 2017 and 31 December 2021. These patients were divided into an in-vitro fertilisation and embryo transfer (IVF-ET) conception group and a natural conception group according to the conception method. The clinical and imaging data were then collected and compared. Results The mean age of the IVF-ET group (n = 13, 31.85 ± 5.84 years) was higher than in the natural conception group (n = 37, 27.05 ± 5.5 years). The proportions of fever, haematogenous TB and extrapulmonary TB in the IVF-ET group (92.31%, 84.62% and 76.92%, respectively) were higher than those in the natural conception group (40.54%,16.22%,27.03%,respectively). The percentage of patients with pregnancy who had intracranial TB (76.9%) in the IVF-ET group was higher than in the natural conception group (10.8%). The percentage of pregnancy terminations in the IVF-ET conception group (84.62%) was higher than in the natural conception group (48.65%). All the above results had statistically significant differences (p < 0.05). Conclusion Overall, IVF-ET conception combined with extensive pulmonary TB lesions lead to heavy systemic toxic symptoms, severe disease and poor pregnancy outcomes. Therefore, screening for TB prior to performing IVF-ET is recommended.https://doi.org/10.1186/s12884-024-06260-1In-vitro fertilisation and embryo transferNatural conceptionPregnancyTuberculosis |
| spellingShingle | Jia-Lu Wei Le Zhang Yan-Ling Xu Wei Gan Min Qi Xu-Wen Fu Xiang Li Case-controlled study of tuberculosis in in-vitro fertilisation-embryo transfer and natural pregnancy BMC Pregnancy and Childbirth In-vitro fertilisation and embryo transfer Natural conception Pregnancy Tuberculosis |
| title | Case-controlled study of tuberculosis in in-vitro fertilisation-embryo transfer and natural pregnancy |
| title_full | Case-controlled study of tuberculosis in in-vitro fertilisation-embryo transfer and natural pregnancy |
| title_fullStr | Case-controlled study of tuberculosis in in-vitro fertilisation-embryo transfer and natural pregnancy |
| title_full_unstemmed | Case-controlled study of tuberculosis in in-vitro fertilisation-embryo transfer and natural pregnancy |
| title_short | Case-controlled study of tuberculosis in in-vitro fertilisation-embryo transfer and natural pregnancy |
| title_sort | case controlled study of tuberculosis in in vitro fertilisation embryo transfer and natural pregnancy |
| topic | In-vitro fertilisation and embryo transfer Natural conception Pregnancy Tuberculosis |
| url | https://doi.org/10.1186/s12884-024-06260-1 |
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