High-resolution volumetric imaging constrains compartmental models to explore synaptic integration and temporal processing by cochlear nucleus globular bushy cells

High-resolution volumetric imaging constrains compartmental models to explore synaptic integration and temporal processing by cochlear nucleus globular bushy cells

Globular bushy cells (GBCs) of the cochlear nucleus play central roles in the temporal processing of sound. Despite investigation over many decades, fundamental questions remain about their dendrite structure, afferent innervation, and integration of synaptic inputs. Here, we use volume electron mic...

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Bibliographic Details
Main Authors: George A Spirou, Matthew Kersting, Sean Carr, Bayan Razzaq, Carolyna Yamamoto Alves Pinto, Mariah Dawson, Mark H Ellisman, Paul B Manis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-06-01
Series:eLife
Subjects:
connectomics
synaptic integration
temporal precision
compartmental modeling
auditory
end bulb of held
Online Access:https://elifesciences.org/articles/83393

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