Guillain-Barre syndrome: An autoimmune disorder post-COVID-19 vaccination?
SARS-CoV-2 causes Coronavirus Disease 2019 (COVID-19), an infectious condition that can present none or one or more of these symptoms: fever, cough, headache, sore throat, loss of taste and smell, aches, fatigue and musculoskeletal pain. For the prevention of COVID-19, there are vaccines available i...
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Format: | Article |
Language: | English |
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Elsevier
2022-12-01
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Series: | Clinical Immunology Communications |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2772613421000147 |
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author | Zafran Khan Ubaid Ahmad Daniya Ualiyeva Obed Boadi Amissah Asaf Khan Zohaib Noor Nasib Zaman |
author_facet | Zafran Khan Ubaid Ahmad Daniya Ualiyeva Obed Boadi Amissah Asaf Khan Zohaib Noor Nasib Zaman |
author_sort | Zafran Khan |
collection | DOAJ |
description | SARS-CoV-2 causes Coronavirus Disease 2019 (COVID-19), an infectious condition that can present none or one or more of these symptoms: fever, cough, headache, sore throat, loss of taste and smell, aches, fatigue and musculoskeletal pain. For the prevention of COVID-19, there are vaccines available including those developed by Pfizer, Moderna, Sinovac, Janssen, and AstraZeneca. Recent evidence has shown that some COVID-19-vaccinated individuals can occasionally develop as a potential side effect Guillain-Barre syndrome (GBS), a severe neurological autoimmune condition in which the immune response against the peripheral nerve system (PNS) can result in significant morbidity. GBS had been linked previously to several viral or bacterial infections, and the finding of GBS after vaccination with certain COVID-19, while rare, should alert medical practitioners for an early diagnosis and targeted treatment. Here we review five cases of GBS that developed in different countries after COVID-19 vaccination. |
first_indexed | 2024-12-11T02:17:27Z |
format | Article |
id | doaj.art-5e16deaa54124071994eed8618f1ff26 |
institution | Directory Open Access Journal |
issn | 2772-6134 |
language | English |
last_indexed | 2024-12-11T02:17:27Z |
publishDate | 2022-12-01 |
publisher | Elsevier |
record_format | Article |
series | Clinical Immunology Communications |
spelling | doaj.art-5e16deaa54124071994eed8618f1ff262022-12-22T01:24:10ZengElsevierClinical Immunology Communications2772-61342022-12-01215Guillain-Barre syndrome: An autoimmune disorder post-COVID-19 vaccination?Zafran Khan0Ubaid Ahmad1Daniya Ualiyeva2Obed Boadi Amissah3Asaf Khan4Zohaib Noor5Nasib Zaman6State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530 China; University of Chinese Academy of Sciences, Beijing 100049, China; Center for Biotechnology and Microbiology, University of Swat, Pakistan; Corresponding authors.Center for Biotechnology and Microbiology, University of Swat, PakistanUniversity of Chinese Academy of Sciences, Beijing 100049, China; Department of Herpetology, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China; Faculty of Biology and Biotechnology, Al-Farabi Kazakh National University, Almaty 050040, Kazakhstan; Corresponding authors.University of Chinese Academy of Sciences, Beijing 100049, ChinaMinistry of Education, Key Laboratory of Cell Activities and Stress Adaptations, School of life sciences, Lanzhou University, 730000 Gansu, ChinaCAS Key Laboratory of Tropical Marine Bio-Resources and Ecology, Guangdong, China; Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, ChinaCenter for Biotechnology and Microbiology, University of Swat, PakistanSARS-CoV-2 causes Coronavirus Disease 2019 (COVID-19), an infectious condition that can present none or one or more of these symptoms: fever, cough, headache, sore throat, loss of taste and smell, aches, fatigue and musculoskeletal pain. For the prevention of COVID-19, there are vaccines available including those developed by Pfizer, Moderna, Sinovac, Janssen, and AstraZeneca. Recent evidence has shown that some COVID-19-vaccinated individuals can occasionally develop as a potential side effect Guillain-Barre syndrome (GBS), a severe neurological autoimmune condition in which the immune response against the peripheral nerve system (PNS) can result in significant morbidity. GBS had been linked previously to several viral or bacterial infections, and the finding of GBS after vaccination with certain COVID-19, while rare, should alert medical practitioners for an early diagnosis and targeted treatment. Here we review five cases of GBS that developed in different countries after COVID-19 vaccination.http://www.sciencedirect.com/science/article/pii/S2772613421000147COVID-19Guillain-Barre syndromeVaccineAutoimmunePfizerModerna |
spellingShingle | Zafran Khan Ubaid Ahmad Daniya Ualiyeva Obed Boadi Amissah Asaf Khan Zohaib Noor Nasib Zaman Guillain-Barre syndrome: An autoimmune disorder post-COVID-19 vaccination? Clinical Immunology Communications COVID-19 Guillain-Barre syndrome Vaccine Autoimmune Pfizer Moderna |
title | Guillain-Barre syndrome: An autoimmune disorder post-COVID-19 vaccination? |
title_full | Guillain-Barre syndrome: An autoimmune disorder post-COVID-19 vaccination? |
title_fullStr | Guillain-Barre syndrome: An autoimmune disorder post-COVID-19 vaccination? |
title_full_unstemmed | Guillain-Barre syndrome: An autoimmune disorder post-COVID-19 vaccination? |
title_short | Guillain-Barre syndrome: An autoimmune disorder post-COVID-19 vaccination? |
title_sort | guillain barre syndrome an autoimmune disorder post covid 19 vaccination |
topic | COVID-19 Guillain-Barre syndrome Vaccine Autoimmune Pfizer Moderna |
url | http://www.sciencedirect.com/science/article/pii/S2772613421000147 |
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