The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study

Objective: The aim of this study is to determine the effect of laser diode as an alternative treat¬ment on liver dysfunction (in vivo study) that is caused by carbofuran using male mice (Mus musculus) strain Balb/C. Materials and Methods: The samples were divided into three groups, namely, Group CL...

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Main Authors: Suryani Dyah Astuti, Vivi Sumanti Victory, Amalia Fitriana Mahmud, Alfian Pramudita Putra, Dwi Winarni
Format: Article
Language:English
Published: Network for the Veterinarians of Bangladesh 2019-12-01
Series:Journal of Advanced Veterinary and Animal Research
Subjects:
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=56313
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author Suryani Dyah Astuti
Vivi Sumanti Victory
Amalia Fitriana Mahmud
Alfian Pramudita Putra
Dwi Winarni
author_facet Suryani Dyah Astuti
Vivi Sumanti Victory
Amalia Fitriana Mahmud
Alfian Pramudita Putra
Dwi Winarni
author_sort Suryani Dyah Astuti
collection DOAJ
description Objective: The aim of this study is to determine the effect of laser diode as an alternative treat¬ment on liver dysfunction (in vivo study) that is caused by carbofuran using male mice (Mus musculus) strain Balb/C. Materials and Methods: The samples were divided into three groups, namely, Group CL (con¬trol group, no treatment), Group C+L (only treated by carbofuran treatment), and Group C+L+ (treatment group, treated by carbofuran and laser-puncture) with five replications each. After being treated, each liver slice of samples was observed using microscope to get the histology result and then scored. Results: Carbofuran contamination can lead to inflammation of cells and necrosis. The histology results and the scoring test showed that the liver cells repair with the energy dose of laser diode at 0.5 and 1.0 Joule. Conclusion: The optimum energy dose in this study was 1.0 Joule which had the closest score of inflammatory cells and necrosis to normal liver cells. [J Adv Vet Anim Res 2019; 6(4.000): 499-505]
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spelling doaj.art-5e1a03ae245d4f83a3882126b8f1337b2022-12-21T18:32:21ZengNetwork for the Veterinarians of BangladeshJournal of Advanced Veterinary and Animal Research2311-77102019-12-016449950510.5455/javar.2019.f37456313The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo studySuryani Dyah Astuti0Vivi Sumanti Victory1Amalia Fitriana Mahmud2Alfian Pramudita Putra3Dwi Winarni4Department of Physics, Faculty of Science and Technology, Universitas Airlangga, Surabaya, East Java 60115, Indonesia Department of Physics, Faculty of Science and Technology, Universitas Airlangga, Surabaya, East Java 60115, Indonesia Department of Physics, Faculty of Science and Technology, Universitas Airlangga, Surabaya, East Java 60115, Indonesia Biomedical Engineering Study Program, Department of Physics, Faculty of Science and Technology, Universitas Airlangga, Surabaya, East Java 60115, Indonesia Department of Biology, Faculty of Science and Technology, Universitas Airlangga, Surabaya, East Java, 60115, Indonesia.Objective: The aim of this study is to determine the effect of laser diode as an alternative treat¬ment on liver dysfunction (in vivo study) that is caused by carbofuran using male mice (Mus musculus) strain Balb/C. Materials and Methods: The samples were divided into three groups, namely, Group CL (con¬trol group, no treatment), Group C+L (only treated by carbofuran treatment), and Group C+L+ (treatment group, treated by carbofuran and laser-puncture) with five replications each. After being treated, each liver slice of samples was observed using microscope to get the histology result and then scored. Results: Carbofuran contamination can lead to inflammation of cells and necrosis. The histology results and the scoring test showed that the liver cells repair with the energy dose of laser diode at 0.5 and 1.0 Joule. Conclusion: The optimum energy dose in this study was 1.0 Joule which had the closest score of inflammatory cells and necrosis to normal liver cells. [J Adv Vet Anim Res 2019; 6(4.000): 499-505]http://www.ejmanager.com/fulltextpdf.php?mno=56313photobiomodulation; laser diode; liver dysfunction; mus musculus
spellingShingle Suryani Dyah Astuti
Vivi Sumanti Victory
Amalia Fitriana Mahmud
Alfian Pramudita Putra
Dwi Winarni
The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study
Journal of Advanced Veterinary and Animal Research
photobiomodulation; laser diode; liver dysfunction; mus musculus
title The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study
title_full The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study
title_fullStr The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study
title_full_unstemmed The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study
title_short The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study
title_sort effects of laser diode treatment on liver dysfunction of mus musculus due to carbofuran exposure an in vivo study
topic photobiomodulation; laser diode; liver dysfunction; mus musculus
url http://www.ejmanager.com/fulltextpdf.php?mno=56313
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