The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study
Objective: The aim of this study is to determine the effect of laser diode as an alternative treat¬ment on liver dysfunction (in vivo study) that is caused by carbofuran using male mice (Mus musculus) strain Balb/C. Materials and Methods: The samples were divided into three groups, namely, Group CL...
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Format: | Article |
Language: | English |
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Network for the Veterinarians of Bangladesh
2019-12-01
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Series: | Journal of Advanced Veterinary and Animal Research |
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Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=56313 |
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author | Suryani Dyah Astuti Vivi Sumanti Victory Amalia Fitriana Mahmud Alfian Pramudita Putra Dwi Winarni |
author_facet | Suryani Dyah Astuti Vivi Sumanti Victory Amalia Fitriana Mahmud Alfian Pramudita Putra Dwi Winarni |
author_sort | Suryani Dyah Astuti |
collection | DOAJ |
description | Objective: The aim of this study is to determine the effect of laser diode as an alternative treat¬ment on liver dysfunction (in vivo study) that is caused by carbofuran using male mice (Mus musculus) strain Balb/C.
Materials and Methods: The samples were divided into three groups, namely, Group CL (con¬trol group, no treatment), Group C+L (only treated by carbofuran treatment), and Group C+L+ (treatment group, treated by carbofuran and laser-puncture) with five replications each. After being treated, each liver slice of samples was observed using microscope to get the histology result and then scored.
Results: Carbofuran contamination can lead to inflammation of cells and necrosis. The histology results and the scoring test showed that the liver cells repair with the energy dose of laser diode at 0.5 and 1.0 Joule.
Conclusion: The optimum energy dose in this study was 1.0 Joule which had the closest score of inflammatory cells and necrosis to normal liver cells. [J Adv Vet Anim Res 2019; 6(4.000): 499-505] |
first_indexed | 2024-12-22T08:36:22Z |
format | Article |
id | doaj.art-5e1a03ae245d4f83a3882126b8f1337b |
institution | Directory Open Access Journal |
issn | 2311-7710 |
language | English |
last_indexed | 2024-12-22T08:36:22Z |
publishDate | 2019-12-01 |
publisher | Network for the Veterinarians of Bangladesh |
record_format | Article |
series | Journal of Advanced Veterinary and Animal Research |
spelling | doaj.art-5e1a03ae245d4f83a3882126b8f1337b2022-12-21T18:32:21ZengNetwork for the Veterinarians of BangladeshJournal of Advanced Veterinary and Animal Research2311-77102019-12-016449950510.5455/javar.2019.f37456313The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo studySuryani Dyah Astuti0Vivi Sumanti Victory1Amalia Fitriana Mahmud2Alfian Pramudita Putra3Dwi Winarni4Department of Physics, Faculty of Science and Technology, Universitas Airlangga, Surabaya, East Java 60115, Indonesia Department of Physics, Faculty of Science and Technology, Universitas Airlangga, Surabaya, East Java 60115, Indonesia Department of Physics, Faculty of Science and Technology, Universitas Airlangga, Surabaya, East Java 60115, Indonesia Biomedical Engineering Study Program, Department of Physics, Faculty of Science and Technology, Universitas Airlangga, Surabaya, East Java 60115, Indonesia Department of Biology, Faculty of Science and Technology, Universitas Airlangga, Surabaya, East Java, 60115, Indonesia.Objective: The aim of this study is to determine the effect of laser diode as an alternative treat¬ment on liver dysfunction (in vivo study) that is caused by carbofuran using male mice (Mus musculus) strain Balb/C. Materials and Methods: The samples were divided into three groups, namely, Group CL (con¬trol group, no treatment), Group C+L (only treated by carbofuran treatment), and Group C+L+ (treatment group, treated by carbofuran and laser-puncture) with five replications each. After being treated, each liver slice of samples was observed using microscope to get the histology result and then scored. Results: Carbofuran contamination can lead to inflammation of cells and necrosis. The histology results and the scoring test showed that the liver cells repair with the energy dose of laser diode at 0.5 and 1.0 Joule. Conclusion: The optimum energy dose in this study was 1.0 Joule which had the closest score of inflammatory cells and necrosis to normal liver cells. [J Adv Vet Anim Res 2019; 6(4.000): 499-505]http://www.ejmanager.com/fulltextpdf.php?mno=56313photobiomodulation; laser diode; liver dysfunction; mus musculus |
spellingShingle | Suryani Dyah Astuti Vivi Sumanti Victory Amalia Fitriana Mahmud Alfian Pramudita Putra Dwi Winarni The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study Journal of Advanced Veterinary and Animal Research photobiomodulation; laser diode; liver dysfunction; mus musculus |
title | The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study |
title_full | The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study |
title_fullStr | The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study |
title_full_unstemmed | The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study |
title_short | The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study |
title_sort | effects of laser diode treatment on liver dysfunction of mus musculus due to carbofuran exposure an in vivo study |
topic | photobiomodulation; laser diode; liver dysfunction; mus musculus |
url | http://www.ejmanager.com/fulltextpdf.php?mno=56313 |
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